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[The assessment of bacterial flora and antibiotic-sensitivity of bacteria isolated from conjunctival sac, skin of the eyelids and inflammatory lesions in patients with acne vulgaris and rosacea]

Przegl Lek. 2007;64(12):991-6

Authors: Kaszuba-Bartkowiak K, Goś R

AIM: To evaluate bacterial flora of conjunctival sac, the skin of the eyelids and inflammatory lesions in patients with acne vulgaris, rosacea and of healthy people. Bacterial colonization of conjunctival sac, the skin of the eyelids and skin lesions is more frequent in patients with acne vulgaris and rosacea. Because antibiotic resistant strains of bacteria are quite often met, it seems important to determine antibiotic-sensitivity of isolated bacteria. MATERIAL AND METHODS: 178 people underwent bacteriological examination of conjunctival sac, skin of the eyelids and skin lesions: 64 patients with acne vulgaris, 59 patients with rosacea and 55 healthy persons. Microorganisms were identified with laboratory techniques with the use of bio-Merieux kits and determination of drug-sensitivity was performed with recognized laboratory techniques. RESULTS: Positive cultures and general frequencies of the isolations were found to be higher in both groups in comparison with the reference group (the group of clinically healthy people). In healthy persons practically the only saprophytic bacteria--the most often S. epidermidis and S. viridans--were isolated. Whereas in patients suffering from acne vulgaris and rosacea the pathogenic bacteria--S. aureus, P. fluorescens, P. acnes, P. aeruginosa--were additionally isolated. Different spectrum of sensitivity to antibiotics of bacteria isolated from conjunctival sac, the skin of the eyelids and skin lesions in the cases of acne vulgaris and rosacea was proved. CONCLUSIONS: 1. In the cases of acne vulgaris the majority of isolated bacteria from conjunctival sac included Streptococcus spp., Staphylococcus spp. and Enterobacteriaceae. 2. In the severe cases of rosacea the main bacteria found in conjunctival sac were S. aureus, S.pyogenes, P.aeruginosa, E. faecalis, A. baumanii, P. fluorescens. 3. Because of changeable drug-sensitivity of bacterial strains, it seems to be necessary to perform individual culture and antibiogram in every patient with inflammatory lesions, in particular in clinically severe and resistant to therapy cases of acne vulgaris and rosacea. 4. The higher frequency of the bacterial colonisations in the conjunctival sac in patients with acne vulgaris and rosacea can be a potential source of ocular infections in the cases of local and systemic disorders of protective mechanisms. 5. Estimation of bacterial flora and antibiotic sensitivity of bacteria isolated from conjunctival sac, the skin of the eyelids and skin lesions should be perform, especially when patients are prepared for eye surgery.

PMID: 18595500 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/entrez/query.f...p;dopt=Abstract = URL to article