Jump to content

PubMed RSS Feed - - Comparative study of some treatment modalities of rosacea.


rss

Recommended Posts

Related Articles

Comparative study of some treatment modalities of rosacea.

J Eur Acad Dermatol Venereol. 2008 Aug 13;

Authors: Mostafa F, El Harras M, Gomaa S, Al Mokadem S, Nassar A, Abdel Gawad E

Background Rosacea is a disease of complex pathogenesis and variable response to various therapeutic methods. Aim of the work To evaluate and compare the efficacy, safety and side effects of some topical lines of treatment of rosacea. Patients and methods The study included 24 patients (23 females and 1 male) with rosacea on the face. They were classified into three groups - each including eight patients (16 face sides) - and treated with one of three topical agents (azelaic acid 20% cream, metronidazole 0.75% cream or permethrin 5% cream) on one side of the face and another one on the other side twice daily for 15 weeks. Results There was a significant improvement of lesions after 15 weeks of topical treatment with the three agents. Azelaic acid cream was significantly more effective on inflammatory lesions but not erythema than the other two creams. Side effects - mostly transient - were observed with topical creams with no significant difference. They included itching, burning sensation, oedema and scales. Patients who used azelaic acid 20% cream were more satisfied than with other modalities. Conclusion Azelaic acid 20% cream provides an effective and safe alternative to metronidazole 0.75% cream or permethrin 5% cream with the added benefit of increased patient satisfaction.

PMID: 18705632 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/entrez/query.f...p;dopt=Abstract = URL to article

Link to comment
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

×
×
  • Create New...