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Chronic Mucocutaneous Candidiasis (CMC) in Demodectic Rosacea

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Scanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor.
Image courtesy of Wikimedia Commons

Chronic Mucocutaneous Candidiasis (CMC) "is an immune disorder of T cells, it is characterized by chronic infections with Candida that are limited to mucosal surfaces, skin, and nails." [1] One report states, "Heterozygous STAT1 gain-of-function (GOF) mutations result in a combined form of immunodeficiency which is the most common genetic cause of chronic mucocutaneous candidiasis (CMC)." [2] This same report connects "chronic demodicosis in the form of a facial papulopustular eruption, blepharitis, and chalazion" with CMC. This could also be described as demodectic rosacea

Candida has been connected to rosacea in at least one paper. [3]

End Notes

[1] Wikipedia

[2] Pediatr Dermatol. 2019 Oct 21;
STAT1 gain-of-function and chronic demodicosis.
Molho-Pessach V, Meltser A, Kamshov A, Ramot Y, Zlotogorski A

[3] Candida Albicans

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