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Acne rosacea associated imatinib mesylate in a gastrointestinal stromal tumor patient.

J Oncol Pharm Pract. 2010 Jun 15;

Authors: Demirci U, Coskun U, Erdem O, Ozturk B, Yilmaz IB, Benekli M, Buyukberber S

Tyrosine kinase inhibitors (TKIs) are targeted treatments for various cancers. Skin toxicities are one of the most common nonhematological side-effects of TKIs. We report an imatinib mesylate (IM) induced hyperpigmented acne rosacea (AR) and sunitinib-induced palmar hyperkeratosis in the case with gastrointestinal stromal tumor. AR was arisen due to the discontinuation of IM. To the best of our knowledge, this kind of cutaneous side-effect with IM has not been documented previously.

PMID: 20551113 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=20551113&dopt=Abstract = URL to article