Guide

Mosquitoes and Virus and Imiquimod Cream As noted in the post on Protozoa and Rosacea, treatment for malaria [protozoa] has improved some cases of rosacea using mepacrine, chloroquine, and hydroxychloroquine. An article published in Science Daily [1] points out, "There are hundreds of viruses spread by biting mosquitoes which can infect humans...At present, there are no anti-viral medicines and few vaccines to help combat these infections." The article discusses using a skin cream with the active ingredient imiquimod and reports, "By applying skin cream after a bite, researchers found that they could pre-emptively activate the immune system's inflammatory response before the virus becomes a problem. The cream encouraged a type of immune cell in the skin, called a macrophage, to suddenly spring into action to fight off the virus before it could spread around the body." Wouldn't it be novel for 10K RRDi members to get together and each donate a dollar and then sponsor a clinical researcher to investigate if using imiquimod as the active ingredient might improve rosacea? Do you think any pharmaceutical company or other rosacea non profit organization would ever investigate this? How do you get 10K RRDi members to come together and all agree that this should be done? Maybe we might learn that some rosaceans somehow apply this imiquimod cream by diluting it with a moisturizer, coconut oil, shea butter, or something to see if this improves their rosacea. If so, then possibly, as this thread points out, could a virus be connected to rosacea? End Notes [1] Mosquito-borne diseases could be prevented by skin cream, Science Daily

Phage injecting its genome into bacteria - image courtesy of Wikimedia Commons Bacteriophage are a particular virus that are included in the human microbiome that "have been used for over 90 years as an alternative to antibiotics in the former Soviet Union and Central Europe as well as in France." Human Microbiome, Brady Barrows Some researchers are trying to find foods that encourage bacteriophage to act as an antibiotic in the gut, for example, stevia, they say as the "most potent prophage inducer" and explains, "The ability to kill specific bacteria, without affecting others, makes these compounds very interesting." "These findings are important. Scientists now know that the microbiome can influence our physical and mental health; it can also cause inflammation and increase cancer risk. If scientists can work out how to alter the microbiome in specific ways, they can, in theory, remove or reduce these risks." Common foods alter gut bacteria by influencing viruses, MedicalNewsToday

"Retinoids have the potential to cause varying degrees of myositis and their rapid identification could prevent major complications." Source

Can Demodex Mites Transfer From Pets to Humans?

Antonia, The general consensus is that the mites on cats or dogs are a different species, however, as pointed out above, scabies and other demodex can infect a human from a pet. There should be more research on this but as it stands now the data shows that the species of mites on humans are different than on pets, generally speaking. Each mammal usually has its own species of demodex mites. The point of this post is that since we do know that mites can travel from pets to humans, there is a possibility that demodex do indeed infect humans from pets. No one certainly wants to be infected with scabies and avoids any contact with an infected human or pet.

I didn't read this till after my previous post. Good you are taking Tumeric and probiotics. Keep taking them.

Not sure which Blueberry Kind bar you are eating but I found the above Nutrition Facts Label to show you how much carbohydrate is in this bar which shows 24 grams in a 35 gram serving. You can subtract the 2.5 grams of dietary fiber since fiber has no significant energy to consider.* So technically the above serving is 21.5 grams of carbohydrate in a 35 gram serving. That means this bar is 61% carbohydrate. This is a high carbohydrate food. When you carefully go through the Nutrition Facts Label for everything you eat in a day, you are probably, without a doubt eating a high carbohydrate diet. There is ample evidence that sugar/carbohydrate is a rosacea trigger in anecdotal reports. For that matter, any proposed rosacea trigger is based upon surveys or anecdotal reports, therefore, listing sugar/carbohydrate as a rosacea trigger is just as valid as any other proposed rosacea trigger, no matter who makes the list. So usually the question is what should you eat for thirty days to see if reducing sugar/carbohydrate improves your skin? Eat high protein and fat. Eating high protein/fat for thirty days poses absolutely no health risk contrary to what you might learn from any source. After the thirty days you can then decide based upon what you learn whether this improves your rosacea and other issues. This will not be easy because sugar is an addiction. So you simply have to balance whether having your skin issues improve is worth the effort to get off of sugar for just thirty days. Also since you are taking doxycycline, you will need to build up your good flora with probiotics, which is now an accepted medical treatment for rosacea. Short term antibiotics for rosacea may be required to control rosacea, but long term antibiotic treatment for rosacea can produce some unwanted side effects and risks. You need to decide whether taking long term antibiotics are worth those side effects and risks. Probiotics offer an alternative. How long did you use Soolantra? Why did you stop using it? It is good you are taking supplements, herbals and vitamins. Have you read this post? Don't give up, you will find a way to control your rosacea and other issues. *To learn why fiber is not a significant source of energy, read the article, Carbohydrate Not Essential For Human Survival

Methanobrevibacter smithii image courtesy of Cedars Sinai Bacteria has been implicated in rosacea with a huge amount of clinical papers on this subject. Demodex is now without a doubt linked to a significant number of rosacea cases. At least one fungus has been associated with rosacea, and we have papers indicating treatment for one particular protozoa improves rosacea, however virus has not been ruled out in rosacea. The human microbiome includes the skin which contains a number of different microbes. [1] One microbe that has generally been totally ignored is archea, which has never been ruled out as having anything to do with rosacea. Archea and Rosacea "Methanobrevibacter smithii is the predominant archaeon in the human gut." The general public has little if any knowledge of this microbe which has been known to exist in the human microbiome for some time now. "Archaea are a major part of Earth's life. They are part of the microbiota of all organisms. In the human microbiota, they are important in the gut, mouth, and on the skin. They may play roles in the carbon cycle and the nitrogen cycle." [2] The chief reason that archea is basically totally ignored as having anything to do with rosacea is that there is no known archea human pathogen. Furthermore, due to the bias the scientific community has towards bacteria which focuses research on bacteria ignoring most of the other microbes, including archea, little is known about archea. "A deeper knowledge of human microbiome composition and microbe-host interactions will contribute to clarify the mechanism of development of rosacea and possibly will provide innovative therapeutic approaches." [3] Basically we have no idea what role archea plays in the skin microbiome due to a lack of investigation into this subject. Hence, little is known of what role archea may play in rosacea. There is absolutely no motive to investigate this since who would fund such a study? Hopefully someday some research will discover the role archea plays in the human microbiome and whatever revelations are discovered may alter our understanding of archea. Do you want to fund such a study? Could 10K members of the RRDi get together and each donate one dollar to fund such a study? Only with your help could we reach such a goal. Think about it. [4] End Notes [1] "Microorganisms inhabiting superficial skin layers are known as skin microbiota and include bacteria, viruses, archaea and fungi." Future Microbiol. 2013 Feb;8(2):209-22. doi: 10.2217/fmb.12.141. Skin microbiota: overview and role in the skin diseases acne vulgaris and rosacea. Murillo N, Raoult D. "In the GI tract, the microbiome is made up of trillions of microbes including bacteria and other microbes such as fungi and archaea. The skin is also colonized by an equally complex microbiome that varies with host genetic and environmental influences. Emerging research suggests that the collection of microbial communities that populate the skin and GI tract, rather than single microorganisms alone, is responsible for disease." Dermatol Pract Concept. 2017;7(4):31–37. Published 2017 Oct 31. doi:10.5826/dpc.0704a08 Diet and rosacea: the role of dietary change in the management of rosacea Emma Weiss and Rajani Katta "Human skin hosts a diverse ecosystem of bacteria, fungi, viruses, mites, and archaea." Skin Microbiota and Your Health, by Chris Kresser, Kresser Institute [2] Archea, Wikipedia [3] Journal of Clinical Gastroenterology 48 Suppl 1, Proceedings From The 7th Probiotics, Prebiotics & New Foods Meeting Held In Rome On September 8-10, 2013:S85-S86 · November 2014; DOI: 10.1097/MCG.0000000000000241 Skin Microbiome and Skin Disease The Example of Rosacea Mauro Picardo [4] More thoughts on this subject to think about:Rosacea Research in Perspective of FundingRosacea Research in Perspective of Idiopathic Diseases

A paper written in 2017 about diet and rosacea never once mentions sugar/carbohydrate as a rosacea trigger and parrots the diet triggers promoted by the NRS while admitting that "Dietary triggers are also frequently cited by patients, although there is a lack of research in this area. In one survey by the National Rosacea Society of over 400 patients, 78% had altered their diet due to rosacea. Of this group, 95% reported a subsequent reduction in flares." The NRS has never listed sugar/carbohydrate as a rosacea trigger, even though the number of anecdotal reports continue to grow that indeed sugar/carbohydrate is just as valid a rosacea trigger as any of the other NRS proposed triggers. The paper about diet and rosacea is cited below: Dermatol Pract Concept. 2017;7(4):31–37. Published 2017 Oct 31. doi:10.5826/dpc.0704a08 Diet and rosacea: the role of dietary change in the management of rosacea Emma Weiss and Rajani Katta

Welcome to the RRDi community support. If you are suffering from rosacea plus gastatory face flushing* and erythromelagia, we can only empathize with your situation. Your condition is extreme and quite unusual. Not many rosaceans are suffering as much as you are suffering. Have you tried avoiding sugar and carbohydrate or at the very least reduced your intake to see if this improves your situation? Sugar is the fire that burns rosacea. It is not expensive to avoid sugar, in fact, you will save money avoiding sugar. Basically, all you do it eat high protein/fat for thirty days to see if your skin improves. Eating high protein/fat for just thirty days and drinking lots of water is not a health risk since it is only temporary. You may learn that you need more protein/fat instead of the high sugar/carbohydrate to control your rosacea. For example, you may not know how eating macaroni and cheese is a high carbohydrate meal. Our bodies are mostly water, protein and fat and carbohydrate only takes a very small percentage of our body mass. It is simply something that you can rule out to see if this helps your skin. In order to recommend topicals, we would need to know what topicals you have tried. Also what oral medications or vitamins/supplements or any other oral treatments have you tried? How long have you been suffering from this? * "Gustatory flushing affects both sides of the face and is associated with excessive salivation, tear production and nasal secretion with no history of parotid gland injury. This may be reproduced by chewing a chilli pepper and holding it in the mouth for 5 minutes." Flushing, DermNet NZ

Belo Essentials Tranexamic +Kojic acid Belo Essential Kojic Acid +Tranexamic Acid Soap Belo Essentials Tranexamic +Kojic acid Intensive Whitening Face And Neck Cream

Colorized electron micrograph showing malaria parasite [protozoa] Image courtesy of Wikimedia Commons Protozoa and rosacea has not been considered in any clinical paper known to date. However, there is a "link between protozoa, vitamin B12 deficiency, acne and depression" according to at least one clinical paper. [1] This same source states the following about rosacea: "Rosacea is another inflammatory skin disease that causes facial redness but it is different from acne, the common denomination being inflammation. Metronidazole, a synthetic antibacterial and antiprotozoal agent of the nitroimidazole class, is used against protozoa such as Trichomonas vaginalis, amebiasis, and giardiasis. Metronidazole is extremely effective against anaerobic bacterial infections and is also used to treat Crohn’s disease, antibiotic-associated diarrhea and rosacea. The nitroimidazoles class of agents used to treat G. lamblia infection includes metronidazole, tinidazole, ornidazole, and secnidazole. This class was discovered in 1955 and was found to be highly effective against several protozoan infections." [1] "Protozoa constitute a group of microorganisms, also known as protists, some of which are responsible for serious diseases in humans, such as malaria and Chagas' disease and inflammatory disease conditions." [1] A significant number of worldwide deaths due to diarrhea are caused by three protozoas - Entamoeba, Cryptosporidium, and Giardia. The human microbiome includes a number of different microbes, including protozoa. The NRS substantiates that protozoa are included in the human microbiome by publishing this statement, "Microbes include bacteria, fungi, protozoa [bold added] and others, and may be found in greatest concentrations in the ears, nose, mouth, vagina, digestive tract, anus and the skin." [2] Very little is known about protozoa and rosacea. What exactly are protozoa? "Protozoa (also protozoan, plural protozoans) is an informal term for single-celled eukaryotes, either free-living or parasitic, which feed on organic matter such as other microorganisms or organic tissues and debris. Historically, the protozoa were regarded as "one-celled animals", because they often possess animal-like behaviors, such as motility and predation, and lack a cell wall, as found in plants and many algae. Although the traditional practice of grouping protozoa with animals is no longer considered valid, the term continues to be used in a loose way to identify single-celled organisms that can move independently and feed by heterotrophy." Wikipedia Treatment Used for Malaria Has Proved Successful in Rosacea There has been some treatments for malaria [protozoa] that have been used to treat rosacea such as mepacrine, artemisinin, artesunate, chloroquine, and hydroxychloroquine that have proved successful in some rosacea patients. Protozoa has never been ruled out as having a connection with rosacea. There simply isn't data on this subject. There needs to be a clinical study done on protozoa and rosacea. Who would fund such a study? Since protozoa has never been ruled out in causing rosacea, who would support such an investigation? Would you? Just think if 10K members of the RRDi each donated one dollar and insisted on supporting a reputable clinician to study protozoa and rosacea, what might be discovered? If you have a comment about this, please find the green reply button and let us know your comment. End Notes [1] Research, September 2015; DOI: 10.13140/RG.2.1.1087.9200 PROTOZOAL LINK BETWEEN SEVERE ACNE, RISK OF ATTEMPTED SUICIDE AND IMMUNE SUPPRESSION: A direct peripheral blood test to confirm microparasitic infections, Beldeu Singh [2] The Ecology Of Your Face: Demodex, Rosacea And You, National Rosacea Society

I hope others try this. I was just pointing out I couldn't find any essential oil available. Are the leaves available for purchase somewhere?

Mepacrine is one of the Anti-parasitic Prescription Agents. There are some papers indicating using mepacrine (Quinacrine) for the treatment of rosacea. One paper published in The Lancet, May 1952 written by Borrie Peter and another paper published in 1955. [1] Another paper mentions using mepacrine and chloroquine in combination to treat rosacea. [2] Anecdotal Reports Here are some anecdotal reports using Mepacrine: lucy_nic87 reports, "i have now been on mepacrine for about 5 weeks and this last week particularly my flushing has been much reduced. my redness is still there, if anything perhaps a bit worse, but i have not had any of that hot feeling, burning, flushing i was having. my skin in general feels calmer. i am however turning rather yellow which can be a side effect for some. if it doesnt get too much worse i can handle it, but it if increases im not sure." lamarr in October 2008 started a thread about Mepacrine. Halfpipe101 in May 2009 started a thread that his flushing is almost cured using Mepacrine. kev711216 in May 2011 started a thread on success using Mepacrine. Ray at RF [post no 14 on 5/22/2011] wrote, "I've been on quinacrine now for 3 months and I'm happy to report I havent flushed once in almost a month. Scarlet Letters has an interesting article discussing using mepacrine and plaquenil in treating rosacea. End Notes [1] The Lancet Volume 259, Issue 6718, 31 May 1952, Page 1113, Letters to the Editor TREATMENT OF ROSACEA WITH MEPACRINE Borrie Peter Science Direct Acta Derm Venereol. 1955;35(6):446-52. Mepacrine in rosacea. INMAN PM, GORDON B. [2] Br J Dermatol. 1955 Dec;67(12):421-5. Mepacrine and chloroquine in the treatment of rosacea. BRODTHAGEN H.

A recent study published by International Immunopharmacology states that hydroxychloroquine "improved rosacea in rosacea-like mice and mast cells (MCs)" and investigated "the effects of HCQ treatment for rosacea patients". The paper concludes, "In vitro, HCQ suppresses LL37-induced MCs activation in vitro, including the release of inflammatory factors, chemotaxis, degranulation and calcium influx. Moreover, HCQ attenuated LL37-mediated MCs activation partly via inhibiting KCa3.1-mediated calcium signaling. Thus, these evidences suggest HCQ ameliorated rosacea-like dermatitis may be by regulating immune response of MCs. Finally, the 8-week HCQ treatment exerted satisfactory therapeutic effects on erythema and inflammatory lesions of rosacea patients, indicating that it is a promising drug for rosacea in clinical treatment." Since hydroxychloroquine is available worldwide in generic form we should hear more reports from rosaceans who will ask their physician for a prescription to confirm these results. Duff Man reported in 2017 that this worked for him. Another thread at RF in 2010/2011 has a few others who have tried it discuss their experience. antwantsclear [post no 240 and post no 243] reports taking hydroxychloroquine starting in 2011 and continues to use it for flushing. One paper published in the Archives of Dermatology, January 2011, indicates that 3 out of 5 patients with neurogenic rosacea were successful using hydroxychloroquine. More Info Hydroxychloroquine is a novel therapeutic approach for rosacea. Plaquenil (Hydroxychloroquine) Mast Cell Stabilizers in the Treatment of Rosacea: A Review of Existing and Emerging Therapies

A paper published in the British Journal of Dermatology concluded that after treatment with 1% and 3% Minocycline Topical Gel, this resulted with a "significantly decreased inflammatory lesion counts and a significantly larger proportion of subjects achieved IGA success at week 12 in the 3% topical minocycline group. These findings support further evaluation of minocycline gel for the treatment of inflammatory lesions associated with papulopustular rosacea." Metronidazole will be having some competition.

* Dry skin (Xeroderma) can be a co-existing condition with rosacea. When treating rosacea with topicals or oral treatments, a common side effect is dry skin, and if one already has dry skin, this complicates and exacerbates the dry skin issue further. "Symptoms most associated with xeroderma are scaling (the visible peeling of the outer skin layer), itching, and skin cracking." Wikipedia "Repeated application (typically over a few days) of emollients or skin lotions/creams to the affected area will likely result in quick alleviation of xeroderma. In particular, application of highly occlusive barriers to moisture, such as petrolatum, vegetable oils/butters, and mineral oil have been shown to provide excellent results. Many individuals find specific commercial skin creams and lotions (often comprising oils, butters, and or waxes emulsified in water) quite effective (although individual preferences and results vary among the wide array of commercially available creams)." Wikipedia Skin Hydration Sensor (SHS) might be used to measure your skin moisture. Treatments The Merck Manual recommends the following: "Frequency of bathing should decrease and tepid, rather than hot, water should be used. Skin moisturizers should be used frequently, particularly immediately after bathing, to decrease transepidermal water loss. Thicker moisturizers such as petrolatum- or oil-based moisturizers are more effective than water-based lotions, although water-based lotions may be better tolerated in warmer climates. Moisturizers with additives such as ceramides, alpha-glycolic acids (eg, lactic, glycolic, and pyruvic acids), and beta-glycolic acids (eg, salicylic acid) are very commonly used. Increasing fluid intake and using humidifiers also help." Xeroderma, Merck Manual Women's Health has an article on treating dry skin using The Inkey List treatments and has this to say about the subject: "Dry skin needs – you guessed it – serious hydration." Adex Gel The following four treatments are recommended: (1) Polyglutamic Acid [1] (2) Squalane Oil [2] (3) Rosehip Oil [3] (4) Lactic Acid [4] "Oral hydration is key but directly hydrating the skin with a solid moisturizer is just as important. You must pick a moisturizer based on your skin type. If you have dry skin use a cream with greater oil content." [5] End Notes [1] Polyglutamic Acid THE INKEY LIST Polyglutamic Acid Polyglutamic Acid Serum [2] Squalane Oil Amara Beauty Squalane Oil The Ordinary 100% Plant-derived Squalane [3] Rosehip Oil Bvokey recommends rosehip oil for rosacea. Eva Naturals Rosehip Seed Oil Kate Blanc Rosehip Seed Oil Leven Rose Rosehip Oil Radha Rosehip Oil Teddie Organics Rosehip Seed Essential Oil The Inkey List Rosehip Oil The Ordinary 100% Organic Cold-Pressed Rose Hip Seed Oil Trilogy Certified Organic Rosehip Oil [4] Lactic Acid The Inkey List Lactic Acid Measurable Difference Lactic Acid Face Serum [5] My skin is as dry as the Mojave, what do I do? By Dr. Ali Tehrani, For the Daily Press Etcetera (Moisturizers) There are a number of other moisturizers to consider in our affiliate store. You may also want to check our forum category on moisturizers. Coconut Oil for Rosacea (as a moisturizer) Bio-Oil *Image [The distribution of the bloodvessels in the skin of the sole of the foot. (Spalteholz.)] Courtesy of Wikimedia Commons

"Allergic reactions in the skin can be caused by many different chemical compounds found in creams, cosmetics, and other topical consumer products, but how they trigger the reaction has remained somewhat mysterious." Study may explain how chemicals in skincare products trigger allergic contact dermatitis, New Medical

Time to review the 2018 Form 990 the NRS publishes on their website or you can read for yourself below (click to open pdf): nrs_990_2018.pdf Review Let's first try to concentrate on the positive aspects of this report. The NRS is the leading non profit organization for rosacea that supports research grants for rosacea. In 2018 a total of $12,500 was spent on research grants if you read Form 990, Part IX, Line 1. How can you figure out who received the $12,500? You definitely have to do some digging since the Form 990 doesn't disclose this. The NRS website in its Awarded Grants page shows Dr. Anna Di Nardo and colleagues were awarded $25,000 in 2018. In reviewing the Form 990 it does indeed show that $25,000 was awarded to the Regents of UCSD shown below: So let's give the NRS a benefit of doubt and instead of $12,500 which is shown on Form 990, Part IX, Line 1, and commend the NRS for spending $25K for rosacea research grants. This means that the NRS spent 5.37% of its donations in 2018 on rosacea research. Putting into Perspective How the NRS Spends Donations 2018 donations were down from previous years with a total revenue of $465,042 (in the 21 years I have been following the NRS Form 990s, 2001 was the only year lower in donations). While acknowledging above that the NRS spent $25K for rosacea research, putting this into perspective is the fact for every dollar donated to the NRS in 2018 only a little more than a nickel (5 cents) was actually spent on rosacea research. What was the rest of the donations spent on? Answer: 93% of the donations were spent on two private contractors that are owned by the president/director of the NRS Sam Huff. Here is a screen shot of the names of the two private contractors shown on Form 990: How do we know that Glendale Communications Group, Inc and Park Mailing and Fulfillment, Inc belong to Sam Huff? The Illinois Secretary of State gives the proof. As you can see from the screen shot above, Form 990, Schedule R, Line 2 shows the amount sent to these two corporations which is $432,408. Is this legal? Yes, of course. You didn't know that NON profit corporations can do this? If you want an education, read this post. Here is a screen shot of Form 990, Part VII, Section A, Compensation which is interesting: I didn't know that Zoe Draelos, MD who also serves on the RRDi MAC is now serving on the board of directors for the NRS. She received $2500 from the NRS in compensation. Good for her! Also Dr. Gallo who I have tried to contact to serve on the RRDi MAC to no avail also received $2500. Good for him! Did you note how much Sam Huff receives? The RRDi would love to give Dr. Draelos $2500 but we didn't even receive half that amount in donations so all we can do is keep our website going and keep the RRDi afloat since our donations are quite meager compared to the donations given to the NRS. One other very interesting item on the 2018 Form 990 the NRS has released is the amount of Excessive Contributions which has never been revealed in the twenty years I have been following NRS Form 990s. See below: If you note the screen shot above it says **Do Not File** ***Not Open to Public Inspection*** which if I had paid accounting fees of $26,691 to my accountant as shown on the NRS Form 990 for 2018, Part IX, Statement of Functional Expenses, Line 11, c, it would pose a question why is this made public? We have never before had any indication the amount of donations the pharmaceutical companies give to the NRS. And if you note in Form 990, Part VI, Governance, Section B, Policies, Line 11a, please note the question, "Has the organization provided a complete copy of this Form 990 to all members of its governing body before filing the form?" and also note that 'yes' was checked. This is also restated in Form 990, Schedule O, where it shows the following line: If the pharmaceutical companies discover that the NRS has disclosed its Schedule A, IDENTIFICATION OF EXCESS CONTRIBUTIONS, what might the consequences of this be? I find it odd in the first place that 501 c 3 non profits are not required to disclose the identification of who is donating when it is obvious they are private contributions and not pubic donations. However, you know who makes the IRS rules for non profits? Probably nothing will become of this disclosure but I find it really interesting. The only other interesting item I found was that the NRS reports an expense of advertising in the amount of $74,814 (Form 990, Part IX, Statement of Functional Expenses, Line 12. It also reports on Form 990, Part VIII, Statement of Revenue, Line 2a, Advertising Income in the amount of $85,000. I don't recall seeing any advertisements on the NRS website, but maybe I am missing something? I wish I could figure out how to get advertising income for the RRDi. Does anyone know how this is done? Sure could use some help. For a spreadsheet of all the years reviewed: click here.

We are accepting articles from novice rosacea sufferers or health professionals on rosacea subjects to be published in the next edition of the Journal of the RRDi. There are no charges for submitting your article. However you will be required to join the RRDi to submit your article by clicking on the Sign up button and membership is a minimum of $2/month (discount to $1/month for three or more months). Our privacy policy is second to none. We are the most private rosacea member forum on the internet with ample security in our member forum. You may follow the two steps below to begin the process to have your article reviewed, approved and published (scroll all the way down to view the TWO STEPS required to submit your article): (1) Step One Sign in or Sign up (RRDi Members Only) Look at the top right corner of your browser and either Sign up (if you have NOT registered, we also now allow Sign in with Apple) or Sign in (if you have already registered) - See screen shots below to understand what to look for to learn how to SIGN UP or scroll further down to see how to SIGN IN: The Sign in process REQUIRES you to confirm your email address. (2) Step Two NOVICE ONLY (Professionals skip this and scroll on down) After you have registered an account and you are a novice and you are logged in, in the same category forum you are in now, ROSACEA RESEARCH, POST your article on rosacea. You are currently in the following category forum: Look for the button START NEW TOPIC (currently a blue button now) and click on it (see screen shot below): Post your rosacea article and this starts the review process for novices only by clicking on the START NEW TOPIC green button. Novices this is all that is required. Professionals follow the directions below. PROFESSIONALS Only follow this step: If you are a professional health care provider, please, Submit your paper using this form. We only accept Google .doc or MS Office Word .docx files, or portable data files (pdf). Please convert your paper to pdf when submitting your paper if you are not using MS Office Microsoft Word. You will be required to have a Google account, either your own Gmail account, or the RRDi will provide a free G Suite account upon request. If you are volunteering on the RRDi MAC a Google Workspace account will automatically be provided for you. All RRDi MAC consultants have been issued a free Google Workspace account and if you need assistance logging into your account contact us for assistance. ISSUES WITH THESE STEPS If you are having any issues with the above steps CONTACT us describing your issue so we can assist you.

There are four Human Herpes Virus known that may have implications with rosacea which should be considered. They are Varicella zoster virus (VZV) (HHV)-3, Epstein-Barr virus (EBV)/ HHV- 4, Cytomegalovirus (CMV)/HHV-5, and Human herpes virus type 6 (HHV-6). [8] If you are suffering with any of these viruses and also have rosacea you may want to ask your physician about antiviral treatment drugs. Virus and Rosacea For more information.

Update of using the ZZ cream. Used one jar of the cosmetic for a month or so and now on the Original ZZ cream again about two weeks in. Here are the results:

Just an update on my venting in this thread, which started on April 8, 2019 (264 days this thread has been up and running) which now has 299 views as of this date (December 28, 2019). I have moved to Alabama and have begun going through the process of registering the RRDi in Alabama which is odd, because I recall one of the members of the board of directors for the Rosacea Research Foundation was a veterinarian living in Alabama. Very few rosaceans will recall all those events back in 2004 when two non profit organizations went in two separate directions. The RRF dissolved but David Pascoe still maintains its website and has now removed the names of those who served on the board of directors. So I put out a request for any member of the RRDi who lives in Alabama to come forward and volunteer to sit on the board of directors and Johannes Schild has filled that spot so that we have two members on the board who are residents of Alabama. We could also continue to be registered in Hawaii if any RRDi member would volunteer to do that, but since volunteering is usually something that our RRDi members shy away from, I doubt if that would ever happen. I personally knew a friend in Hawaii who has rosacea and asked her to do that but she told me she was also leaving Hawaii next year and couldn't volunteer. So if anyone wants to keep the RRDi registered in Hawaii it would be good to contact me asap. So this thread has had an average of just a little over 1 view a day since I initially posted my vent. Not too many care about reading my vent, and at least Apurva has replied to this thread (and I am happy for almost 300 views). However, I will continue my vent. Could one of you who reads this thread explain to me why you think hardly any of the RRDi members don't want to post in the public forum? Why would 1200 plus members join the RRDi and then NEVER post? What is going on? I thought since Facebook and Reddit were PRIVATE (social media groups for rosacea) and for some reason rosaceans prefer to be in private groups, the RRDi has sponsored a private rosaceans group but that has NOT been popular at all. We are spending $10/month to do this and it sure hasn't been used at all. I was thinking about making the public member forum we use through Invision Community into a PRIVATE forum. What are your thoughts about this? The RRDi does have Facebook and Reddit groups but that hasn't proved popular at all. What are your thoughts about all this? Why the lack of posting by RRDi members?

Demodex Canis image courtesy of Wikimedia Commons Many 'authorities' say that mites on pets do not transfer to humans [1], but this is another example of the 'butterfly effect' in rosacea. While generally speaking mites on pets don't transfer to humans, we demonstrate with references that this myth is officially debunked. Most clinical papers on rosacea refer to only two demodex mite species found in humans, demodex folliculorum and demodex brevis. For example, Wired magazine in its article on demodex reports, "Our network of skin caverns offers food and shelter to two different species of mites: Demodex folliculorum and Demodex brevis." However, there are a large range of demodex mite species, one source says, "approximately 50,000 species have been described." [2] In dogs there are at least three types of demodex, Demodex canis, D. injai and D. cornei. [3] There are different species of mites living on birds and rodents. In fact, just about all mammals have some species of demodex mites living on them. Can any of these mites, especially on pets transfer to humans? The answer is yes. In rare cases this happens with various mites. In the case of scabies it is common. "Humans occasionally become infested with zoonotic mites, which can cause discomfort and dermatitis. A few species can transmit diseases, such as human vesicular rickettsiosis. Mites from animals do not usually survive for very long on humans, and most zoonotic infestations are self-limiting...Some mites do not cause any apparent ill effects unless their population becomes unusually large. Other species, such as Sarcoptes scabiei, can result in clinical signs even when only a few mites are present...However, humans can be infested transiently by the scabies mites of a wide variety of domesticated and exotic animals, as well as by Notoedres cati. and Trixacarus caviae....Myobia musculi, Radfordia affinis and Radfordia ensifera (family Myobiidae) affect rodents. The eggs of myobiid mites are usually attached to the base of the hair on the host. These mites feed on tissue fluids, but can also feed on blood from capillaries at the surface of the skin. They are readily transmitted between hosts, and may also infest cats, dogs and people...Human infestations with mites such as Cheyletiella and Sarcoptes scabiei are reported occasionally. The transmission rate for S scabiei var canis from dogs to people is estimated to be 10-50%, and close, prolonged skin contact is the most important route of transmission. Cheyletiella mites from animals are also reported to bite humans readily; however, clinical signs may not be common, or possibly not recognized." [2] "A twenty-year-old girl student who feeds a Miniature Pinscher crossbred dog in her house for a while noticed common itchy papulopustular lesions, incrustation and some alopecic loci in her dog and admitted to Selçuk University Faculty of Veterinary Medicine, Department of Parasitology. Itchy papules and pustules were also observed in dog's owner face and arm about three or four weeks later. Skin scrapings and hair samples were taken from the patient and the dog and examined with light microscope. Adult and egg forms of Demodex spp. were detected in both patient and dog specimens in microscopic examination." [4] "Mange is a skin disease that is caused by two different species of mites. Sarcoptic mange is caused by Sarcoptes scabiei. Demodectic mange can be caused by several mites of the Demodex family. Sarcoptic mange is extremely itchy and highly contagious to other animals and humans. Demodectic mange is not as itchy, and while it can be transmitted to other dogs, it is not contagious to humans or cats." [5] "Scabies, an infestation by the itch or scabies mite, Sarcoptes scabiei var. hominis, remains a major public health problem worldwide and a common cause of PUO in returning travelers. The worldwide prevalence of scabies has been estimated to be about 300 million cases/y. Although more often associated with crowding, homelessness, institutionalization, and immunodeficiency, scabies occurs worldwide in both sexes, at all ages, and among all ethnic and socioeconomic groups." [6] "Sarcoptes scabiei or the itch mite is a parasitic mite (an arthropod) that burrows into skin and causes scabies. The mite is found in all parts of the world. Humans are not the only mammals that can become infected. Other mammals, such as wild and domesticated dogs and cats (in which it is one cause of mange) as well as ungulates, wild boars, bovids, wombats, koalas, and great apes are affected." Wikipedia "Although host specific cross infections between humans and animals have been rarely reported, D. canis was determined to be more transmissible across species than the other Demodex mites as indicated in the literature. As a result, it is necessary and important to keep in mind about Demodex spp. infestation in patients with skin complaints and pet feeding." [7] "Two different mange mites cause skin disease in dogs. Although both share certain characteristics, it is important not to confuse the two types of mange, because they have different causes and treatments, and one can be passed to humans. The two types are demodectic mange, caused by the mite Demodex canis and sometimes just called demodex, and sarcoptic mange, caused by infestation of the mite Sarcoptes scabiei and sometimes called scabies...The sarcoptic mange mite can be transmitted to humans who come into contact with a dog infested with sarcoptes." [7] "The parasite [Sarcoptes scabiei] can be transmitted from dog to dog and can pass from dogs to humans, although it doesn’t thrive on non-canine hosts." [8] "Although dogs and humans live in close contact, there have beenfew reports suggesting transmission of dog mites to their own-ers, and to our knowledge, none that definitively confirmed that the mites found on the human patient were D. canis and not D. folliculorum or D. brevis. However, the patients involved were younger than would be expected for detectable Demodex presence. In addition, D. canis was found to survive and repro-duce in dog skin engrafted onto SCID mice, but did not spreadto the surrounding mouse skin. [9] Conclusion Generally speaking it is rare for humans to contact mites from pets, but it can happen as the above sources cited indicate. Usually, the only species of demodex mites found on humans are demodex folliculorum and demodex brevis, but in some rare cases cited above, other mite species are found, with the exception of scabies, as noted above, which effects millions of humans. Anecdotal Evidence This thread started by soapbubble1 is anecdotal evidence establishing demodectic transfer in humans. If you have further anecdotal evidence why not find the reply button and post your experience. Etcetera What is the difference between demodex, dust mites, bed bugs and scabies? Demodex Update Why do demodex like human skin? Reply to this Topic There is a reply to this topic button somewhere on the device you are reading this post. If you never heard about this topic and you learned about it here first, wouldn't it be a gracious act on your part to show your appreciation for this topic by registering with just your email address and show your appreciation with a post? And if registering is too much to ask, could you post your appreciation for this topic by finding the START NEW TOPIC button in our guest forum where you don't have to register? We know how many have viewed this topic because our forum software shows the number of views. However, most rosaceans don't engage or show their appreciation for our website and the RRDi would simply ask that you show your appreciation, please, simply by a post. End Notes [1] There are several examples of this, for example the Miami Herald has an an article entitled, Mange mites not transmittable between dogs and humans. The Illinois Department of Public Health has an article on mites and states, "Most mites never come in contact with humans, but some that do can affect a person’s health." The article does not mention demodex mites. Mites Affecting Humans "No, demodectic mange is not contagious to other animals or humans." Demodectic Mange in Dogs, Ernest Ward, DVM; Updated by Amy Panning, DVM, VCA Hospitals "Additionally, demodex mites found on cats and dogs do not spread to humans." Feline Demodex, Catherine Barnette, DVM, VCA Hospitals [2] Acariasis, Mange and Other Mite Infestations, June 2012 The Center for Food Security and Public Health, Institute for International Cooperation in Animal Biologics, College of Veterinary Medicine, Iowa State University [3] Demodex canis, Arachnida, Canine Parasites and Parasitic Diseases, Science Direct [4] Mikrobiyol Bul. 2018 Apr;52(2):214-220. doi: 10.5578/mb.66410. [A dog related Demodex spp. infestation in a student: a rare Demodex case]. Esenkaya Taşbent F, Dik B. [5] Mange in Dogs a.k.a. Sarcoptic mange, Demodectic mange, scabies, etc PETCOACH EDITORIAL [6] Journal of Travel Medicine, Volume 17, Issue 1, 1 January 2010, Pages 21–31, Mite‐Transmitted Dermatoses and Infectious Diseases in Returning Travelers James H. Diaz, MD, MPH&TM, Dr PH [7] Dog mange called scabies can transfer to humans, Dr. Wes Borgman, Orlando Sentinel [8] Mange: What You Need to Know, Mar Bovsun, American Kennel Club [9] Journal of European Academy of Dermatology and Venereology [Full Text]Demodex: a skin resident in man and his best friendR. Foley, P. Kelly, S. Gatault, F. Powell