Guide

Van Gogh - Trauernder alter Mann image courtesy of Wikimedia Commons "The study found that people stigmatized by rosacea: are embarrassed by their skin condition (77 per cent); have difficulty establishing new relationships (53 per cent); avoid public contact or cancel social engagements (54 per cent); get depressed (70 per cent); lose confidence (69 per cent); and feel frustrated and angry (74 per cent). Rosacea also negatively affected their sex life, family life, work life, mood and psychological condition." Study confirms the emotional pain rosacea inflicts, says Windsor dermatologist, Brian Cross, CTV Windsor [1] "Skin diseases, especially those with visible manifestation, are considered to cause a major influence on global mental health. Therefore, we determined the prevalence and severity of anxiety, depression, and suicidal ideation in a large sample of patients with facial dermatoses, namely acne, rosacea, folliculitis, and perioral dermatitis....Acne and rosacea are associated with anxiety, depression, and suicidal ideation in Lithuanian patients. Younger patients are more prone to report such symptoms than older ones." [2] "Moreover, patients with rosacea are more likely to be depressed, have social phobias, and have an overall higher perception of their disease." [3] Etcetera Use your finger, cursor or mouse with this image. Enjoy. Reply to this Topic There is a reply to this topic button somewhere on the device you are reading this post. End Notes [1] J Eur Acad Dermatol Venereol., 21 June 2016 Feelings of stigmatization in patients with rosacea B. Halioua, B. Cribier, M. Frey, J. Tan Other articles by J Tan: J Eur Acad Dermatol Venereol. 2016 Mar;30(3):428-34. doi: 10.1111/jdv.13556. Prevalence of rosacea in the general population of Germany and Russia - The RISE study. Tan J, Schöfer H, Araviiskaia E, Audibert F, Kerrouche N, Berg M; RISE study group. Journal of the American Academy of Dermatology Volume 69, Issue 6, Supplement 1, December 2013, Pages S27-S35 Rosacea: Current state of epidemiology JerryTan MD, Mats Berg MD ---------------------------------------------------------------- [2] Dermatology. 2020 Apr 06;:1-9 Anxiety, Depression, and Suicidal Ideation amongst Patients with Facial Dermatoses (Acne, Rosacea, Perioral Dermatitis, and Folliculitis) in Lithuania. Lukaviciute L, Ganceviciene R, Navickas P, Navickas A, Grigaitiene J, Zouboulis CC [3] Clin Cosmet Investig Dermatol. 2021; 14: 601–614. Updates and Best Practices in the Management of Facial Erythema Jameson Loyal, Emily Carr, Rawaa Almukhtar, Mitchel P Goldman

Interview on CTV Windsor

Thanks for you post. That is what the RRDi is all about, a huge database of rosacea information to educate rosaceans. The treatments that don't work need to be flagged by posting a user experience. A treatment that does works needs to be shared. The RRDi has the means to contact any member by email address to confirm that the user is an actual rosacea sufferer and if the poster doesn't respond to the inquiry then the user can be banned. This isn't being done in rosacea groups on Facebook, Twitter or other social media (the posts could be spam and very little is being done to prevent spam). The RRDi has safeguards in place to prevent spammers and trollers who prey on rosacea sufferers.

So going to the gym or exercising to increase muscle mass may improve your rosacea. Just about any physician will tell you that exercise and eating healthy will improve not only health but also your rosacea.

Dr. Chris Steele talks about LDN.

Updated this post in December 2020 with a Video, so please click here to view. Below is what I wrote in 2019. I continue to use this thread and posted on February 2, 2021, Groundhog Day, an update even though the link to the video/post on this subject above has a lot of information on this subject especially for those of you who don't like to read and love videos. For those of you who still read, you may find this thread interesting. If you do, could you be gracious and post your comment in this thread? If you scroll through the thread you will see my more recent thoughts on this subject and possibly some other rosaceans might add their thoughts, but gaining the trust of rosaceans has now proved to be a daunting task, just to get their trust to post on our website. ------------------------------------------------ That has been my question for a number of years when I noticed no activity here at the RRDi, even though having over 1200 members, hardly anyone posts. I have thought during this time obviously rosaceans prefer social media over the forum style posting that has been around for twenty years, which doesn't have the user experience they are accustomed to using social media platforms. I have been browsing and posting a little at Facebook, Reddit, and Twitter and found that the level of education about rosacea is paltry and mostly these groups of rosaceans are into horse paste. They feel very comfortable showing horrible photos of their rosacea which I find really ironic since I heard so many complaints about joining the RRDi and filling out contact information (so we dropped the requirement and only require an email address). The lack of knowledge about rosacea in these social media groups and the spam posts allowed for all sorts of treatment for rosacea, not to mention the advertising, to me is a sad choice rosaceans have made instead of joining together in to a non profit organization for patient advocacy. At least I know where the rosaceans have gone. Very sad.

Low Dose Naltrexone (LDN) "Naltrexone, sold under the brand names ReVia and Vivitrol among others, is a medication primarily used to manage alcohol or opioid dependence." It also "has been used in chronic pain such as fibromyalgia with new but well documented evidence of potential benefit." [1] There are anecdotal reports that it reduces flushing, neuropathic rosacea, neurogenic rosacea, and improves phenotype 1. Flugs at RF has started a thread indicating that low dose Naltrexone helps with phenotype 1 (of course Flugs calls it subtype 1). If you read the entire thread Flugs also takes propranolol (10 mg 3 times daily ), uses IPL (post no 29), however, in post no 49 Flugs writes, "I’ve also dropped all the meds I have tried in the past, none of which seemed to help much anyway... at least not enough for me to want to do something to my heart in order to help my face. So all I’m taking now is LDN and a tablesppon of apple cider vinegar every day." Flugs reports at post no 80, "On the down side though - I have to confess that i have had a few (pretty minor) flushes in the past two or three weeks. Almost always for no apparent reasons. It may still be post IPL recovery, last one was a month ago.. but IPL recoveries used to be waaaayyy worse, so if this is all I get I'm fine with that. I confess I have also been dabbling with (very mild) mandelic acid of late - I think I was overdoing it - Ive dialled back." So Flugs is still trying some other treatments along with LDN. In post 99 he mentions his 12th IPL treatment. At post no 112 Flugs writes, "I am still prone to flushing a little when I get too warm - and also (oddly) when I am trying, and failing, not to fall asleep, such as late at night in front of the tv (that’s always made me flush.. does that happen with anyone else!?) when I say “flushing a little” I mean that my cheeks get red and feel warm, but I can take it down pretty much instantly by cooling them (fan, water spray etc) in some way. Even if I were to leave them be they would go down themselves within a few mins... compare that to the sometimes 12 hour long painful flushes I got when the rosacea arrived two years ago." Judworth who suffers from Neuropathic Rosacea (has lots of posts) reports in the same thread Flug started mentioned above about his experience taking LDN, "Since taking LDN I am cautiously happy to report that I haven't had any facial nerve pain, I still get the warm room flush, but my face is less reactive in general, even after a spell on the computer (which always gave me an element of activity even if it wasn't a full-blown flush)." At post no 117 Judworth writes, "LDN has been a god-send for me, not only calming the skin, stopping my facial nerve pain and halting the burning sensation in my mouth caused by lichen planus, I feel it is somehow re-booting my faulty immune system!" At post no 567, "my flushing has been knocked out by about 99%." Judy says that the LDN sublingual drops is preferred at post no 3 in this thread. Sineadrosy started a thread on this subject with other discussing their experience. One paper says LDN is a treatment also for pain. [2] Dosage The low dose Naltrexone is usually starting out at 1 mg and gradually increasing to 4.5 mg. Flugs insists that taking more than this won't work (go through his thread which has many other users reporting success with LDN). Etcetera You may want to show your doctor this pdf: Low-dose Naltrexone (LDN) Fact Sheet 2014 LDN Research Trust LDNNow End Notes [1] Naltrexone, Wikipedia [2] New hope for treating chronic pain without opioids, ScienceDaily We have a post on LDN in other prescriptions. Reply to this Topic There is a reply to this topic button somewhere on the device you are reading this post. If you never heard about this topic and you learned about it here first, wouldn't it be a gracious act on your part to show your appreciation for this topic by registering with just your email address and show your appreciation with a post? And if registering is too much to ask, could you post your appreciation for this topic by finding the START NEW TOPIC button in our guest forum where you don't have to register? We know how many have viewed this topic because our forum software shows the number of views. However, most rosaceans don't engage or show their appreciation for our website and the RRDi would simply ask that you show your appreciation, please, simply by a post.

image courtesy of IMDB Canadian Egyptian actress Christine Solomon has rosacea. She is reported as stating, "I purchased acne products off the shelf, and that turned out to be a big mistake! My cheeks became inflamed because of the ingredients in those products, and my condition worsened. That’s when I consulted a dermatologist for the first time, and he diagnosed me with rosacea at the age of 14 years old." Ms Solomon is the 2018 spokesperson for the Acne and Rosacea Society of Canada’s Rosacea Awareness Campaign. Canadian Egyptian Actress On Rosacea, Acne and Rosacea Society of Canada Famous Rosaceans

Tom Busby, SD poster extraordinare at RF, mentioned in a post on this subject at RF, "an alternative source of ivermectin, on eBay" which is ivermectin powder. I asked Tom whether this would be a good idea since it seems a lot safer to use the horse paste than have to concoct a paste with grain alcohol and his comment is, "horse paste is fairly expensive for a really tiny amount of product.... I have to assume that someone who has some experience formulating hot emulsions (oil in water) could make a non-greasy cream with this ivermectin powder." You might prefer the horse paste for a trial run before purchasing a chemistry set to make this. And of course you would have to know the formulae to be able to take a gram of ivermectin and dilute it to 1% with grain alcohol which is 100 parts grain alcohol to 1 part ivermectin and be able to dissolve it correctly into a cream base. Most rosaceans are not into a laboratory approach to treatment preferring a pill or a topical than experimenting with such treatments in a lab coat. But, of course, this is the internet, and guess what? Watch Mr. Wizard concoct a new rosacea treatment on YouTube (maybe we will hear reports of this). Also, if you haven't heard of the new TXA treatment, it also requires concocting a rosacea treatment yourself by purchasing powder from Amazon or your local chemical store. The RRDi recommends you check with your physician before using ivermectin for rosacea.

Evidence for a genetic component to rosacea has been hypothesized, with a retrospective study showing that rosacea patients have a greater than fourfold increased odds of having a family member with rosacea (Abram et al., 2010; Steinhoff et al., 2013), but the genes leading to this association are not known....A genome-wide association study was conducted in 22,952 individuals whose genomes showed >97% European ancestry. Because of the sample size needed for this study, cases and controls were identified by an online questionnaire in which participants responded to a survey item on whether a healthcare professional had ever diagnosed them with rosacea. Participants who answered “yes” were defined as “cases” (n=2,618), and those who answered “no” (n=20,334) were defined as “controls”.... Together, these data strongly suggest a role for antigen presentation by class II HLA in the etiology of rosacea. The data presented from this large discovery and replication group provide evidence for a genetic component of rosacea. J Invest Dermatol. 2015 Jun; 135(6): 1548–1555. Assessment of the Genetic Basis of Rosacea by Genome-Wide Association Study Anne Lynn S Chang, Inbar Raber, Jin Xu, Rui Li, Robert Spitale, Julia Chen, Amy K Kiefer, Chao Tian, Nicholas K Eriksson, David A Hinds, and Joyce Y Tung

Watch the Video Systemic Cormobidities Rosacea is associated with a number of other diseases, referred to as ‘systemic comorbidities’, which one study reports, “Clinicians must be aware of the potential for systemic comorbidities in rosacea patients, which becomes more likely as disease duration and severity increase.” [1] However, one paper cautions, "Rosacea may be a proxy for systemic disease, rather than a mere skin disorder, as it has been linked with metabolic, cardiovascular, autoimmune, and chronic kidney diseases. However, most of the relevant data are from epidemiologic studies without basic experimental details. Thus, further evidence must be sought to support the hypothesis that rosacea is associated with systemic inflammation and systemic diseases." [15] Furthermore, "It may be recommended that clinicians pay careful attention to the clinical follow-up of these patients to avoid missed associated comorbidities." [17] "Clinicians should acknowledge these interrelations and employ comprehensive care with an individual-based approach." [25] These systemic comorbidities are in addition to a number of co-existing conditions with rosacea. This is a controversial subject but clinical papers on this subject continue to be published. For example, this paper indicates "evidence on the association between rosacea and several systemic diseases." [32] "Some of the identified pathways link rosacea with its systemic comorbidities, including atherosclerosis (ICAM1, angiotensinogen, and HMGB1), Alzheimer’s disease (DHCR24 and myeloperoxidase), dementia (PRNP), and Parkinson’s disease (SNCA, HSPA8, and GSK3B), indicating that therapeutic maintenance of rosacea might protect from the development of rosacea-associated cardiovascular and neurological diseases." [34] The following is a growing list which we are updating as more data is investigated and published that state rosacea is associated with other diseases: Alcohol Abuse [25] Allergic Conjunctivitis [25] Allergic Rhinitis [25] Allergies (airborne, food, etc.) Alopecia Areata [25] Alopecia (Frontal fibrosing) [21] Alzheimer's Disease Ankylosing Spondylitis [25] Anxiety Disorder [3] Anxiety and Depression Atherosclerosis [33] Autoimmune conditions [2] [29] Autoimmune Thyroiditis [25] Autosensitization dermatitis Blepharitis [29] Body Mass Index (BMI) values higher Breast cancer [20] Cancer [12] Cardiometabolic Syndrome Cardiovascular diseases and risk [3] [26] Celiac Disease [28] Chalazion [29] Cholesterol (higher total) [22] [23] Chronic inflammatory skin diseases (CISD) [18] Chronic Mucocutaneous Candidiasis (CMC) Chronic rhinosinusitis (CRS) [4] [25] CKD Conjunctivitis [29] COPD [31] Crohn Disease [19] Dementia [24] Depression/anxiety disorders [3] [24] Dental foci of infection [13] Diabetes [3] Diabetes Mellitus [25] Dry Eye Disease (DED) Dry Eye Syndrome [29] Dyslipidemia [3] [22] [23] Dysregulation of the innate and adaptive immune responses [16] Female hormone imbalance [5] [10] [14] Frontal fibrosing alopecia Fibromylgia syndrome (FMS) Gastroesophageal Reflux Disease (GERD) and other GI disorders [1] [14] [25] [28] Gastrointestinal disease [14] Glaucoma [29] Glioma Glucose (blood glucose higher} [22] Hair loss Helicobacter pylori infection [3] [28] Hepatobiliary Cancer [25] Hepatobiliary system disorders [1] Herpes Infection [25] Higher Systolic Blood Pressure [26] HLA-DRA Locus [7] Human Papillomavirus Infection [25] Hepatobiliary Cancer [25] Hyperglycemia [27] Hyperlipidemia [3] [14] Hypertension [6] [14] [20] [22] [23] Hyperthyroidism [20] [24] [29] Inflammatory Bowel Disease (IBD) [19] [28] Irritable Bowel Syndrome [24] [25] Kidney Disease [8] Low-density lipoprotein (LDL) is higher [22] [23] Low-grade inflammation Lung Cancer [25] Meibomian gland dysfunction Melasma [20] Mental Health Disorders [9] Metabolic diseases [1] [14] Metabolic Syndrome [23] MetS Migraine Multiple sclerosis Obesity [25] Obstructive Sleep Apnea Parkinson's disease Peptic ulcers [20] Proton Pump Inhibitors Psychiatric diseases [3] Respiratory diseases [1] [14] [31] Raynaud syndrome Rheumatoid Arthritis [3] [25] Serum Uric Acid levels higher (Serum UA and CRP values higher) SIBO [19] [28] Sleep Sjögren syndrome [25] Smoking Systemic Sclerosis [25] Teeth and Gum Issues Thyroiditis [25] Triglycerides are higher (TG) [22] Ulcerative Colitis [3] [24] Urogenital diseases [10] [14] [24] Venous Thromboembolism Vitiligo [25] Virus More Research Needed Since the above list keeps growing this complicates the theories on the cause of rosacea increasing the call for further research. For example, in one study it was stated, "In this large study of patients with rosacea, atopic dermatitis, and psoriasis, we did not detect an increased 1-year risk of cardiovascular disease after adjusting for confounders." [11] Wouldn't this call for more independent research funded by rosaceans since "further evidence must be sought to support the hypothesis that rosacea is associated with systemic inflammation and systemic diseases" ? [15] Confounding Factors Therefore, papers stating an association of rosacea with other diseases should all be taken with a grain of salt due to 'confounders' since another paper states, "Limitations included the accuracy of the published data, potential patient selection, and possible confounding factors. The true nature of the drawn correlations is uncertain, and causality cannot be established." [3] [bold added for emphasis] image courtesy of WikiMedia Commons "In statistics, a confounder (also confounding variable, confounding factor or lurking variable) is a variable that influences both the dependent variable and independent variable causing a spurious association." Wikipedia Reply to this Topic There is a reply to this topic button somewhere on the device you are reading this post. End Notes [1] Int J Dermatol. 2018 Dec 21;: Systemic comorbidities associated with rosacea: a multicentric retrospective observational study. Aksoy B, Ekiz Ö, Unal E, Ozaydin Yavuz G, Gonul M, Kulcu Cakmak S, Polat M, Bilgic Ö, Baykal Selcuk L, Unal I, Karadag AS, Kilic A, Balta I, Kutlu Ö, Uzuncakmak TK, Gunduz K [2] Dermatol Clin. 2018 Apr;36(2):115-122. doi: 10.1016/j.det.2017.11.006. Epub 2017 Nov 29. Rosacea Comorbidities. Vera N, Patel NU, Seminario-Vidal L. [3] J Am Acad Dermatol. 2018 Apr;78(4):786-792.e8. doi: 10.1016/j.jaad.2017.09.016. Epub 2017 Oct 26. Comorbidities in rosacea: A systematic review and update. Haber R, El Gemayel M. Anais Brasileiros de Dermatologia Rosacea associated with increased risk of generalized anxiety disorder: a case-control study of prevalence and risk of anxiety in patients with rosacea Pinar Incel Uysal, Neslihan Akdogan, Basak Yalcin One report states, "The pooled analysis found no association between rosacea prevalence and the incidence of CVDs...However, no association was found between rosacea and diabetes mellitus...We found no association between rosacea and high-density lipoprotein cholesterol...or triglycerides..." Biomed Res Int. 2020;2020:7015249 Association between Rosacea and Cardiovascular Diseases and Related Risk Factors: A Systematic Review and Meta-Analysis. Li Y, Guo L, Hao D, Li X, Wang Y, Jiang X J Cosmet Dermatol. 2020 Dec 21;: Association between rosacea and cardiovascular disease: A systematic review and meta-analysis. Zhang J, Yan Y, Jiang P, Liu Z, Liu Y, Liu Y, Wang X, Li M, Xu Y [4] There may be a relationship between rosacea and chronic rhinosinusitis (CRS) as the following quote concludes: "Patients with rosacea and CRS manifested severe erythematotelangiectatic rosacea. There was enough evidence to suggest an association between rosacea and CRS. Clinical and radiological assessments of the paranasal sinuses are recommended." Med Princ Pract 2014;23:511-516 (DOI:10.1159/000364905) Rosacea and Chronic Rhinosinusitis: A Case-Controlled Study Al-Balbeesi A.O. Department of Dermatology, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia [5] "There is no research regarding hormones and their effect on rosacea," Dr. Bergfeld said. "However, it has been widely observed that rosacea is often aggravated at menopause and sometimes during mid-cycle." Women May Need Added Therapy, Rosacea Review, NRS [6] Cardiovascular Diseases and Rosacea [7] "The HLA-DRA locus is associated with rosacea as well as with other inflammation-associated disorders, such as inflammatory bowel diseases including ulcerative colitis, Crohn’s disease, and celiac disease....Moreover, Spoendlin et al. found that an increased risk of rosacea was observed particularly during the period of increased gastrointestinal tract inflammation. Thus, the overlap in the genetic relevance of HLA-DRA between rosacea and inflammatory bowel diseases might imply a potential link between these disorders...Patients with rosacea have a higher risk of cardiovascular comorbidities including hypertension, dyslipidemia, and coronary artery disease than that seen in controls. Rosacea severity was also found to be dependent on the presence of cardiovascular comorbidities....In addition, the association between cardiovascular diseases and rosacea might also be explained by enhanced expression of the cathelicidin, which has been observed both in the course of atherosclerosis and rosacea. The GWAS by Chang et al. [20] also revealed that patients with rosacea shared a genetic locus with type 1 diabetes mellitus; this association was further confirmed by a population-based study as well....Patients with rosacea have a significantly increased risk of neurologic disorders such as migraine, depression, complex regional pain syndrome, and glioma...Recently, an increased interest has been shown in the potential associations between neurodegenerative diseases and rosacea....For example,...Parkinson’s disease...dementia, especially Alzheimer disease..." Int J Mol Sci. 2016 Sep; 17(9): 1562. Published online 2016 Sep 15. doi: 10.3390/ijms17091562, PMCID: PMC5037831 Rosacea: Molecular Mechanisms and Management of a Chronic Cutaneous Inflammatory Condition Yu Ri Woo, Ji Hong Lim, Dae Ho Cho, and Hyun Jeong Park, Chris Jackson, Academic Editor [8] Study Finds Possible Link Between Kidney Disease and Rosacea, NRS [9] Clin Exp Dermatol. 2019 Jan 31;: The mental health burden in acne vulgaris and rosacea: an analysis of the US National Inpatient Sample. Singam V, Rastogi S, Patel KR, Lee HH, Silverberg JI [10] J Am Acad Dermatol. 2015 Aug 6; Rosacea is associated with chronic systemic diseases in a skin severity-dependent manner: Results of a case-control study. Rainer BM, Fischer AH, Luz Felipe da Silva D, Kang S, Chien AL [11] Dermatol Ther (Heidelb). 2016 Dec;6(4):649-658. Epub 2016 Sep 22. Cardiovascular Disease Outcomes Associated with Three Major Inflammatory Dermatologic Diseases: A Propensity-Matched Case Control Study. Marshall VD, Moustafa F, Hawkins SD, Balkrishnan R, Feldman SR, [12] J Dermatol. 2019 May 23;: Potential association between rosacea and cancer: A study in a medical center in southern China. Long J, Li J, Yuan X, Tang Y, Deng Z, Xu S, Zhang Y, Xie H "The current literature shows that rosacea is significantly associated with increased odds of nonmelanoma skin cancers, glioma, and breast cancer." Rosacea and Its Association With Malignancy: Systematic Review [13] Gen Dent. 2019 Nov-Dec;67(6):52-54 Association of dental foci of infection and rosacea: a case report. Sopi M, Meqa K [14] Rosacea Linked to Various Conditions, Including Respiratory, GI Disease, Infectious Disease Advisor [15] Dermatology 2019;235:255–259 DOI: 10.1159/000496968 Characterization of the Blood Microbiota in Korean Females with Rosacea Yeojun Yun, Han-Na Kim, Yoosoo Chang, Yunho Lee, Seungho Ryu, Hocheol Shin, Won-Serk Kim, Hyung- Lae Kim, Jae-Hui Nam [16] J Eur Acad Dermatol Venereol. 2020 Jan 28;: Rosacea as a striking feature in family members with a STAT1 gain-of-function mutation. Sáez-de-Ocariz M, Suárez-Gutiérrez M, Migaud M, O Farrill-Romanillos P, Casanova JL, Segura-Mendez NH, Orozco-Covarrubias L, Espinosa-Padilla SE, Puel A, Blancas-Galicia L [17] Arch Dermatol Res. 2020 Feb 04;: Evaluation of serum uric acid levels in patients with rosacea. Karaosmanoglu N, Karaaslan E, Ozdemir Cetinkaya P See also Immune System Disorder [18] "Conversely, the mean estimated 10-year survival was higher in pemphigus (P = 0.0451), lichen planus (P = 0.0352), rosacea (P < 0.0001), lower in bullous pemphigoid and dermatomyositis (P < 0.0001), and similar in atopic dermatitis, alopecia areata, and hidradenitis suppurativa compared to psoriasis." [bold added] Arch Dermatol Res. 2020 Feb 11;: Multimorbidity and mortality risk in hospitalized adults with chronic inflammatory skin disease in the United States. Narla S, Silverberg JI [19] Helicobacter pylori infection but not small intestinal bacterial overgrowth may play a pathogenic role in rosacea AG Gravina, A Federico, E Ruocco, A Lo Schiavo, M Masarone, C Tuccillo, F Peccerillo, A Miranda, L Romano, C de Sio, I de Sio,1 M Persico, V Ruocco, G Riegler, C Loguercio, and M Romano Medicine. 98(41):e16448, OCTOBER 2019 DOI: 10.1097/MD.0000000000016448 , PMID: 31593075 Issn Print: 0025-7974 Association of rosacea with inflammatory bowel disease: A MOOSE-compliant meta-analysis Fang-Ying Wang;Ching-Chi Chi; [20] J Dermatol. 2020 Mar 24;: Epidemiological features of rosacea in Changsha, China: A population-based, cross-sectional study. Li J, Wang B, Deng Y, Shi W, Jian D, Liu F, Huang Y, Tang Y, Zhao Z, Huang X, Li J, Xie H [21] "Facial papules were more common in younger patients and both facial papules and rosacea were associated with a greater need for oral treatment." Actas Dermosifiliogr. 2020 May 14;: Frontal Fibrosing Alopecia: A Retrospective Study of 75 Patients. Maldonado Cid P, Leis Dosil VM, Garrido Gutiérrez C, Salinas Moreno S, Thuissard Vasallo IJ, Andreu Vázquez C, Díaz Díaz RM [22] J Am Acad Dermatol. 2020 Apr 28;: Association between Rosacea and Cardiometabolic Disease: A Systematic Review and Meta-Analysis. Chen Q, Shi X, Tang Y, Wang B, Xie HF, Shi W, Li J [23] Biomed Res Int. 2020;2020:7015249 Association between Rosacea and Cardiovascular Diseases and Related Risk Factors: A Systematic Review and Meta-Analysis. Li Y, Guo L, Hao D, Li X, Wang Y, Jiang X J Am Acad Dermatol. 2021 Jan 30;: Reply to: "Implementing the association between rosacea, hypertension, and dyslipidemia in clinical practice". Chen Q, Tang Y, Li J Indian J Dermatol. 2021 May-Jun; 66(3): 302–307. Skin and Metabolic Syndrome: An Evidence Based Comprehensive Review Farhat Fatima, Anupam Das, Piyush Kumar, and Debatri Datta [24] J Clin Aesthet Dermatol. 2020 Jul;13(7):36-40 Rosacea and Associated Comorbidities: A Google Search Trends Analysis. Marchitto MC, Chien AL [25] J Clin Med. 2020 Oct 17;9(10): Systemic Comorbidities in Korean Patients with Rosacea: Results from a Multi-Institutional Case-Control Study. Woo YR, Kim HS, Lee SH, Ju HJ, Bae JM, Cho SH, Lee JD [26] Acta Derm Venereol. 2020 Oct 19;: Cardiovascular Risk and Comorbidities in Patients with Rosacea: A Systematic Review and Meta-analysis. Tsai TY, Chiang YY, Huang YC [27] "Patients with rosacea also have a higher incidence of hyperglycemia, which means increased risk of SIBO due to gut hypomotility. Again, the flushing and erythrosis seen in many rosacea patients could be due to the release of angiogenic and vasoactive agents including nitric oxide or TNF-α. The fact is that papulopustular rosacea and erythrotic rosacea could be due to different causes." [bold added] Rosacea and Small Intestinal Bacterial Overgrowth (SIBO), By Liji Thomas, MD, News Medical [28] "In addition, a case–control study demonstrated that patients with rosacea had a twofold odds for prevalent CeD compared with age, sex, and calendar time-matched controls (OR 2.03, 95% CI 1.35–3.07), and stratification by gender revealed a significant association of rosacea with CeD in women, but not in men." Adv Ther. 2021 Jan 28;: Rosacea, Germs, and Bowels: A Review on Gastrointestinal Comorbidities and Gut-Skin Axis of Rosacea. Wang FY, Chi CC Helicobacter pylori infection but not small intestinal bacterial overgrowth may play a pathogenic role in rosacea AG Gravina, A Federico, E Ruocco, A Lo Schiavo, M Masarone, C Tuccillo, F Peccerillo, A Miranda, L Romano, C de Sio, I de Sio,1 M Persico, V Ruocco, G Riegler, C Loguercio, and M Romano [29] Ocular Comorbidities in Rosacea: A Case-Control Study Based on Seven Institutions [30] Assessment of thyroid disorders in patients with rosacea: a large case-control study [31[ Relationship between rosacea and chronic obstructive pulmonary disease: Rosacea and comorbidities [32] Rosacea, not just skin deep: Understanding the systemic disease burden [33] PubMed RSS Feed - -Evaluation of atherosclerotic risk in rosacea patients through serum fetuin-A and carotid intima media thickness [34] Flushing New Light on Rosacea

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The above report was done with 'questionnaires' and was not done with placebo controlled double blind studies. Again, the above study on diet and rosacea is simply anecdotal reports. Another point to question is, does the tea consumed by the respondents to the 'questionnaire' have sugar or not? Wouldn't it be an incredible accomplishment if 10K rosaceans got together and unitedly sponsored an investigative research study on diet and rosacea and actually conducted a clinical study with placebo controlled, double or triple blind controls with a peer reviewed process on this subject. If each rosacean donated $1 and we all agreed this is what we want investigated, do you think that one of the RRDi MAC members might be encouraged to do such an investigation if we sponsored such a study? You try to get 10K members to do this. I have been trying for seventeen years.

"We found that high-frequency intake of fatty food and tea presented a positive correlation with rosacea, while high-frequency dairy product intake showed significant negative correlation with rosacea. Sweet food, coffee and spicy food appeared to be independent of any subset of rosacea in our study. However, high-frequency dairy product intake showed a borderline beneficial effect on rosacea severity. We further analyzed the correlation between diet and the subtype of rosacea. We found that high-frequency fatty intake was associated with erythematotelangiectatic rosacea (ETR) and phymatous rosacea, while high-frequency tea intake was only associated with ETR. In addition, high-frequency dairy product intake showed negative correlations with ETR and papulopustular rosacea. Rosacea is associated with some dietary factors, and our study is valuable in establishing dietary guidelines to prevent and improve rosacea." [1] Did you notice a paradox with the two statements on intake of dairy product? 'while high-frequency dairy product intake showed significant negative correlation with rosacea' 'high-frequency dairy product intake showed a borderline beneficial effect on rosacea severity' Maybe something is lost in translation? This one statement takes the cake with the following statement: 'Sweet food, coffee and spicy food appeared to be independent of any subset of rosacea in our study.' At least one statement we can agree upon, "Rosacea is associated with some dietary factors." Reply to this Topic There is a reply to this topic button somewhere on the device you are reading this post. If you never heard about this topic and you learned about it here first, wouldn't it be a gracious act on your part to show your appreciation for this topic by registering with just your email address and show your appreciation with a post? And if registering is too much to ask, could you post your appreciation for this topic by finding the START NEW TOPIC button in our guest forum where you don't have to register? We know how many have viewed this topic because our forum software shows the number of views. However, most rosaceans don't engage or show their appreciation for our website and the RRDi would simply ask that you show your appreciation, please, simply by a post. End Notes [1] J Dermatol. 2019 Jan 18. doi: 10.1111/1346-8138.14771. Relationship between rosacea and dietary factors: A multicenter retrospective case-control survey. Yuan X, Huang X, Wang B, Huang YX, Zhang YY, Tang Y, Yang JY, Chen Q, Jian D, Xie HF, Shi W, Li J.

Carnivore Diet Food Pyramid image courtesy of 15 Months On The Carnivore Diet: Curing My Hip Arthritis And Upending Everything I Believed About Nutrition (Bloodwork Results Included!), David Eisner, Medium A post by johny at RF recommends a trial diet using the principles of the 'carnivore diet' and states, " if you have decades long skin problems, you probably have issues with plant material. The best evidence is to trial the diet and see for yourself, if you give it an honest effort and don't like it no harm done." A thirty to ninety day trial diet cannot do any permanent damage no matter what proof you come up with, you can always go back to the way you were eating before the trial, and as johny points out, 'no harm done.' There is a huge number of links in a google search on 'carnivore diet' and after reading several articles on this subject, I liked the one by Dave Asprey, Carnivore Diet Results: Why It Works for Some People But Didn’t for Me, who tried eating the carnivore diet for three months, and did notice some improvement which is noted in his article (no mention of rosacea, his improvements included "felt great for the first month") and then explains why modifying the carnivore diet with some tweaks to improve it. Sugar and Carbohydrate are rosacea triggers and any diet that reduces these two items will improve rosacea. Maybe the carnivore diet is something you can at least try and report in this thread your results. Reply to this Topic There is a reply to this topic button somewhere on the device you are reading this post. If you never heard about this topic and you learned about it here first, wouldn't it be a gracious act on your part to show your appreciation for this topic by registering with just your email address and show your appreciation with a post? And if registering is too much to ask, could you post your appreciation for this topic by finding the START NEW TOPIC button in our guest forum where you don't have to register? We know how many have viewed this topic because our forum software shows the number of views. However, most rosaceans don't engage or show their appreciation for our website and the RRDi would simply ask that you show your appreciation, please, simply by a post.

Medical News Today has an article by Christian Nordqvist on rosacea [1] that is fairly comprehensive and takes about five minutes to read but isn't keeping up with the phenotype classification of rosacea, refers to 14 million Americans having rosacea (current estimates are 16 million Americans or 415 million worldwide), doesn't get into the many theories on the cause of rosacea, instead discusses five 'factors' that are thought to contribute to rosacea. The article should be updated and I give it a grade C for reporting and keeping up with rosacea. End Notes What is rosacea? Last updated Fri 15 December 2017 By Christian Nordqvist, Reviewed by Cynthia Cobb, APRN, Medical News Today

Steroid Rosacea image credit: Corinna Kennedy own work 2017 image courtesy of Wikimedia Commons

Dr. Eric Berg explains why MSM and Grapefruit Seed Extract Oil are beneficial for rosacea. Gold Standard Organic Sulfur Crystals • Gold Standard Liquid MSM Drops with Vitamin C Reply to this Topic There is a reply to this topic button somewhere on the device you are reading this post. If you never heard about this topic and you learned about it here first, wouldn't it be a gracious act on your part to show your appreciation for this topic by registering with just your email address and show your appreciation with a post? And if registering is too much to ask, could you post your appreciation for this topic by finding the START NEW TOPIC button in our guest forum where you don't have to register? We know how many have viewed this topic because our forum software shows the number of views. However, most rosaceans don't engage or show their appreciation for our website and the RRDi would simply ask that you show your appreciation, please, simply by a post.

Horse Paste for Rosacea The RRDi recommends you discuss with your physician any questions before using a veterinary treatment for horses for your rosacea. However, the positive reports of using horse paste are growing exponentially and we would be remiss if we didn't discuss it in this thread. Please read through every post in this thread to be up to date on this subject. Add your experience using horse paste in this thread or complete our poll. "Rosacea appears to be the first human skin disease to be treated with a veterinary medication....Doctors and researchers have growing concerns about the widespread use of this homegrown treatment." [1] First and foremost is to understand that you apply the horse paste TOPICALLY on your face at night just before bed and leave it on all night and wash it off in the am. During the day you can apply your favorite moisturizer if you have dry skin or use nothing if you have oily skin. Even though this horse paste is to be used for horses orally, just remember it is for a 1250 pound horse, so it would probably be a terrible idea to ingest the horse paste in a human, so please apply treatment topically. We have a post about taking oral ivermectin, so this thread is about using the horse paste topically. There is one published paper that compares the treatment of using oral ivermectin alone with taking oral ivermectin and oral metronidazole for rosacea which you may not know about. Ivermectin is one of the 'wonder drugs' and a Nobel Prize was awarded for this discovery. For more information on the history of ivermectin. Many report topical horse paste improves Phenotype 2 and Phenotype 4. Paste or Gel? Just about all the brands designate the medium as a paste, but typically there are reports indicating that the substance that comes out appears as a gel. For example, one of the more popular brands is Durvet Horse Paste yet when you observe what comes out of the syringe it is a clear gel. Why the Durvet brand call it a paste (which anyone knows a paste is not translucent) instead of a gel is a question not easily answered. It is possible that the other brands are actually a paste. What is your experience? Is your brand a paste or a gel? Why Horse Paste Rather than Soolantra The chief reasons Rosaceans are using horse paste are the following; (1) cheaper, a gram of horse paste cost approximately $1.16/gram while Soolantra costs approximately $13/gram (Six doses of Durvet Horse Paste at Amazon costs about $20 [six doses include 36 grams which is only 55 cents per gram] and lasts approximately six weeks which should be enough to know if it works better than Soolantra), (2) Horse paste is stronger than Soolantra, horse paste is 1.87% ivermectin while Soolantra is 1% ivermectin, (3) the inactive ingredients in certain brands of horse paste are generally more tolerated than the inactive ingredients in Soolantra (some complain of the 'Cetaphil' base ingredients of Soolantra called the 'basis for the vehicle') and, (4) there are way more positive reports using horse paste than the positive reports of using Soolantra, but, of course, no real data on this, just a cursory overall view of the reports indicate that horse paste is working better than Sooantra, or at the very least, just as good as Soolantra. Galderma may see this success and, in the future, make an ivermectin gel similar to horse paste with fewer inactive ingredients than Soolantra. Galderma knows about the success of horse paste and will without a doubt offer a gel with fewer inactive ingredients as the basis for vehicle as a counter measure and another choice for patients to consider. Watch and see. History One early report of using horse paste for rosacea may have occurred in 2015, which was a reference to Agri-Mectin. A typical example is a post at Facebook, who writes, "I did a full 12 week course of horse paste and yes if you don't dilute it with moisturizer, some do experience headaches. I did not. I also took it by the recommendation of my primary care and dermatologist. My dermatologist recommends it to all of his patients that can not afford Soolantra or have health insurance. He has had many patients that have had success stories with it. And says that horse paste and Soolantra are basically the same thing except hp is a tad stronger and the base ingredients are not as toxic as Soolantra. If you want to try it, I suggest doing a test spot first for a couple days." A Reddit a poster writes, "I called my dermatologist to ask about switching from metronidazole to ivermectin and she actually brought up the idea of trying horse paste before I even mentioned anything! She said she doesn't like to prescribe Soolantra because it's so expensive and recommends the horse paste to patients very often. So relieved to have dermatologist approval on this and thought I'd share because I know there are a lot of folks who are skeptical about trying this method since it isn't 'pharmaceutical grade.' " A poster at Facebook posts, "So I went for my routine Botox session and the staff was amazed at how clear my face was from 3 months ago. My doc was so intrigued by me telling her it was horse paste. She was in shock by the results. She took me around the office showing everyone that this horse paste had cleared my skin. She said she is going to tell a few of her patients about it on the down low! She very excited for me!" You can read about all this in a Reddit group r/rosacea or in the Facebook Group Rosacea (English) and this is spreading in other groups. Therefore, the rosaceans who are trying this over-the-counter treatment for horses on their rosacea while reporting success are the first guinea pigs who have valiantly gone where no rosaceans have gone before and will eventually in the future report back any of the side effects and long term results or risks associated with using a veterinary oral medication for horses on their rosacea topically. It would be ironic that using a horse paste for rosacea that costs a few dollars is just as valid as using Soolantra which has cost millions of dollars for Galderma to go through the hoops to get FDA approval for human use topically. The side effects whether short or long term may be simply the same as Soolantra. The results are speaking for themselves, horse paste is improving rosacea and the news is spreading. Topical Application NOT Oral Ivermectin This post is about topical horse paste for rosacea, NOT oral ivermectin. You will note when visiting the RRDi website we repeat many points over and over and this obviously because repetition is the mother of retention and to really emphasize a point. Brands There are many brands of horse paste and many who report using HP don't mention which brand they are using. Some of more popular brands are Durvet (on the box it says 'paste' but is appears to be a gel), Agri-Mectin, Zimecterin, Noromectin, Horse Health, Durmectin, Bimectin and the list keeps growing. Inactive Ingredients As Tom Busby, mentions in a post at RF referred to in the next comment in this thread (scroll to the next comment) that a valid point is, "The biggest problem with horse paste is that no one knows what the other 98.13% of the ingredients are." The MSDS lists from some brands of horse paste usually do not list the inactive ingredients but some do. We have been investigating and found three brands that actually publish the inactive ingredients, Agri-Mectin, Eqvalan and Normectin (scroll below for more information). AGRI-MECTIN (ivermectin) Paste 1.87% Inactive Ingredients The MSDS sheet for AGRI-MECTIN (ivermectin) Paste 1.87% are the following: Corn Oil, Polysorbate 80, Apple Flavor, and Aerosil. Durvet Inactive Ingredients The box on Durvet clearly says the active ingredient is 1.87% Ivermectin. The MSDS sheet for Durvet Ivermectin Paste does NOT list the inactive ingredients, nor does the detail sheet provided by Durvet. This sheet provided by Bimeda, the parent company of Durvet, simply says the inactive ingredients are Proprietary Component A (80.98%), Proprietary Component B (7.65%), and Proprietary Component C (7.5%). At least we know there are three inactive ingredients but what these ingredients are exactly is still a mystery. Horse Health Equine Ivermectin Paste 1.87% The MSDS sheet for Horse Health Equine Ivermectin Paste 1.87% doesn't show the inactive ingredients. Eqvalan However, in the third post in this thread we now have the inactive ingredient list for another horse paste, Eqvalan which are listed below: Eqvalan Oral Paste for Horses Ingredients: Ivermectin: 1.87% w/w. Titanium Dioxide (E171) 2.0% w/w.HyproloseHydrogenated Castor OilPropylene Glycol Bimectin The inactive ingredients are listed as Proprietary Component A (80.98%), Proprietary Component B (7.65%), and Proprietary Component C (7.5%) on this data sheet. Bimectin-Paste_Bimeda_112015_SDS.pdf Duramectin The data sheet for Durvet DuraMectin Ivermectin Paste 1.87% does NOT list the inactive ingredients: duramectinMSDS.pdf Zimecterin The inactive ingredients are not known. First Companion Iverchoice Equine Paste The inactive ingredients are not known. Farnam IverCare (ivermectin paste) The inactive ingredients are not known. Vetrimec Paste (Ivermectin 1.87%) MSDS doesn't list the inactive ingredients. For more information. Brochure . Noromectin (available in the UK) Noromectin is available in the UK and Europe at the Prequine (GREVELING HOLDING BV) website, a company in the Netherlands (the inactive ingredients are not available and one product insert shows the ivermectin contains 0.08% w/v and 3.0% v/v Benzyl Alcohol as an excepient ). The product sheet below indicates this while the package box shows 1.87% which is odd. NOROMECTIN-PASTE.pdf Another website shows 1.87% ivermectin, the Norbrook site which is a company in Ireland. It provides a Summary of Product Characteristics which shows a 'List of excipients' which are the following: Hydroxypropyl Cellulose Hydogenated Castor Oil Titanium Dioxide (E171) Propylene Glycol Water for Injection A pdf is provided for your benefit below: SPC_179110.pdf Do It Yourself ElaineA has a Homemade Ivermectin Cream Recipe. End Notes [1] Articles on the internet from reputable sources are publishing news on this subject. The quote is from the first article below. People are turning to medication made for horses to treat rosacea, and dermatologists are concerned, J.K. Trotter, Insider Br J Dermatol. 2018 Dec 30. doi: 10.1111/bjd.17540. Misuse of veterinary wormers in self-medication of rosacea and scabies. Hellen R, Ní Raghallaigh S. Here are other articles mentioning this subject from other reputable sources: "In a recent bulletin in the peer-reviewed British Journal of Dermatology, two Irish dermatologists, Rebecca Hellen and Siona Ni Raghallaigh, described a patient who 'enquired about the use of horse wormer as a cheaper alternative.' " People are turning to medication made for horses to treat rosacea, and dermatologists are concerned, J.K. TROTTER, Business Insider Two dermatologists are quoted as concerned about using horse paste in the following article: People are treating their rosacea with cheap horse medicine, and dermatologists are saying, 'Whoa!', by Bailey King, FEBRUARY 06, 2019. Philly Voice "Physicians are growing concerned about horse paste’s rising popularity. Although it’s cheaper, it hasn’t been tested on humans, and it contains almost double the dosage of ivermectin (1.87 percent versus Soolantra’s 1 percent). Margo Weishar, MD, a cosmetic dermatologist based outside of Philadelphia, says that horse paste “may be irritating, cause allergy, or worse when applied to skin.” People are Using Horse Paste to Treat Rosacea, Julie Morse on February 8, 2019, dermRounds, Dermatology Network "Dermatologists are alarmed with the growing popularity of the inexpensive horse medicine. People cannot be blamed because healthcare is becoming very expensive." Instead Of Makeup, People Are Treating Rosacea With Horse Medicine, Christopher Levay, MiseryWatch Can You Use $5 Horse Paste to Treat Rosacea?, Blog, Leslie Baumann, MD, Cosmetic Dermatologist Br J Dermatol. 2019 Apr;180(4):955. doi: 10.1111/bjd.17540. Epub 2019 Jan 15. Misuse of veterinary wormers in self-medication of rosacea and scabies R Hellen, S Ní Raghallaigh [2] Clin Cosmet Investig Dermatol. 2016; 9: 71–77. New developments in the treatment of rosacea – role of once-daily ivermectin cream Leah A Cardwell, Hossein Alinia, Sara Moradi Tuchayi, and Steven R Feldman [3] Less Expensive Alternative To Soolantra, The Rosacea Forum, post no 8 by fanugi Cost Durvet Ivermectin costs less than $7 for 6 grams ($1.16/gram) while Soolantra costs $390 for 30 grams ($13/gram). Horse Paste brand price varies but typically between $5 and $12 per 6 gram dose. You can save money if you purchase multiple doses (see pricing on three, six and twelve doses by scrolling to the bottom of this post and looking for the Amazon banners). For example, six doses of Durvet costs about $20 which includes 36 grams which is a cost per gram of about 55 cents per gram (a fifty percent savings over buying one dose). The cost savings over Soolantra is one of the principle reasons rosaceans are reporting using horse paste, not to mention the reports that is works better or just as good as Soolantra. Here are the links: Save on Multiple Doses Three Doses Six Doses 12 Doses

Beauty blogger Stephanie Lange has a YouTube channel with a lot of followers has rosacea. She posted on Facebook, "I had a bad flare up of rosacea so I thought instead of hiding - what better way to test out the new @deciem The Ordinary Coverage Foundation!" She has a video, How to Cover Redness / Rosecea / Acne / Inflammation with Makeup you can watch below: Famous Rosaceans Reply to this Topic There is a reply to this topic button somewhere on the device you are reading this post. If you never heard about this topic and you learned about it here first, wouldn't it be a gracious act on your part to show your appreciation for this topic by registering with just your email address and show your appreciation with a post? And if registering is too much to ask, could you post your appreciation for this topic by finding the START NEW TOPIC button in our guest forum where you don't have to register? We know how many have viewed this topic because our forum software shows the number of views. However, most rosaceans don't engage or show their appreciation for our website and the RRDi would simply ask that you show your appreciation, please, simply by a post.

Beauty blogger Casey Holmes has rosacea according to Devon Abelman, allure, in an article, Casey Holmes Shares the Inside Scoop on Her Smashbox Spotlight Palettes, where Casey is quoted as saying, "Since I have a lot of texture and pretty big pores because I have rosacea, I wanted a formula that was very smooth...." Casey has a lot of followers in her YouTube channel and she has a Vlog. Famous Rosaceans Reply to this Topic There is a reply to this topic button somewhere on the device you are reading this post. If you never heard about this topic and you learned about it here first, wouldn't it be a gracious act on your part to show your appreciation for this topic by registering with just your email address and show your appreciation with a post? And if registering is too much to ask, could you post your appreciation for this topic by finding the START NEW TOPIC button in our guest forum where you don't have to register? We know how many have viewed this topic because our forum software shows the number of views. However, most rosaceans don't engage or show their appreciation for our website and the RRDi would simply ask that you show your appreciation, please, simply by a post.

Cæcilie Johansen, MD, who has rosacea explains in details makeup and medicine for rosacea. Zoe Draelos, MD, volunteers for the RRDi MAC, is also the editor of Cosmetic Dermatology and has advice on cosmetics for rosacea. Dr. Sherry Shieh has some advice on what should be in your cosmetic medicine cabinet. Jamie Kern Lima, the co-founder and CEO of IT Cosmetics has rosacea. Beauty bloggers Casey Holmes and Stephanie Lange both have rosacea. There are a number of cosmetic posts for rosacea for your consideration that may prove helpful to you, not to mention our affiliate store has a whole cosmetic category (our non profit organization for rosacea receives a small fee if you purchase a cosmetic for your rosacea which keeps our web site going). We have an informative article about cosmetics and rosacea. Green is the color concealer of choice for rosacea. "Compared with control subjects, rosacea patients were statistically more likely to have positive patch tests. The most common allergens giving positive results were octyl gallate (10.68%), dodecyl gallate (8.74%), tert-Butylhydroquinone (7.77%), thimerosal (6.80%), euxyl K400 (6.80%), cocamidopropyl betaine (5.83%), and 2,6-Di-tert-butyl-4-cresol (4.85%)....This study shows that rosacea patients show a strikingly high prevalence of contact sensitization to cosmetic allergens. We recommend the additional use of cosmetic series for patch testing, and the careful use of cosmetics in rosacea patients if cosmetic contact sensitivity is suspected." Source "Excessive use of facial cleanser (twice or more a day) and facial mask (more than 4 times a week), frequent makeup (more than 6 times a week), regular skin care in beauty salon (more than once a week), and using beauty salon products were closely correlated to the development of rosacea in Chinese population." [1] It is important to be sure you don't irritate rosacea sensitive skin with cosmetics and pick the right ones for your particular skin issues so that it helps and not further damages your sensitive skin. Less is more when it comes to cosmetics and the right cosmetic is just what you need. "The tested corrective cosmetic significantly improved the QOL of subjects with significant facial flaws, skin tautness and dryness, and was well tolerated." [2] "Allergic contact dermatitis to cosmetics (ACDC) complicates the diagnosis and treatment of rosacea, and is increasingly observed in daily practice....Preservatives and fragrances are primary culprits for ACDC in Chinese female rosacea patients." [3] The RRDi has collected a number of cosmetics to consider in your search by using our affiliate store. Reply to this Topic There is a reply to this topic button somewhere on the device you are reading this post. End Notes [1] PLoS One. 2020;15(4):e0231078 Effects of skin care habits on the development of rosacea: A multi-center retrospective case-control survey in Chinese population. Huang YX, Li J, Zhao ZX, Zheng BL, Deng YX, Shi W, Steinhoff M, Xie HF [2] Clin Cosmet Investig Dermatol. 2020;13:253-257 A Corrective Cosmetic Improves the Quality of Life and Skin Quality of Subjects with Facial Blemishes Caused by Skin Disorders. Andra C, Suwalska A, Dumitrescu AM, Kerob D, Delva C, Hasse-Cieślińska M, Solymosi A, Arenbergerova M [3] J Cosmet Dermatol. 2020 Dec 22;: Contact sensitization to cosmetic series of allergens in female patients with rosacea: A prospective controlled study in China. Chen B, Yu F, Chen W, Yao Z, Yang X, Zhang D, Hao F

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