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Given the evidence for an increased risk of GI disease in rosacea, further research into the role of the microbiome in rosacea is warranted. The role of the gut microbiome is an area of research of multiple inflammatory skin diseases. Synbiotics are a combination of prebiotics and probiotics, substances that support a healthy gut microbiome. In a meta-analysis of published randomized controlled trials (RCTs) in atopic dermatitis (AD), it was found that the use of synbiotics for at least eight weeks had a significant effect on a measure of AD severity. Research is underway into the use of synbiotics in other inflammatory skin diseases. Diet and rosacea: the role of dietary change in the management of rosacea.

"The association between inflammatory bowel disease (IBD) and rosacea is another topic of interest. A Taiwanese nationwide cohort study of over 89,000 patients with rosacea found an independent association with IBD incidence, as compared to matched controls. This association has been replicated by Egeberg et al.’s Danish study and Li et al.’s prospective study in American women. Moreover, both IBD and rosacea share possible genetic overlap on the histocompatibility complex class II gene HLA DRB1*03:01." Diet and rosacea: the role of dietary change in the management of rosacea. "In conclusion, our study demonstrates a modest association of rosacea with prevalent and incident IBD. Conversely, another study has shown that IBD is associated with an increase in rosacea.[68] Putting together the evidence, rosacea and IBD are related to each other. When rosacea patients suffer from chronic abdominal pain, prolonged diarrhea, and bloody stool, the possibility of comorbid IBD should be considered." Medicine: October 2019 - Volume 98 - Issue 41 - p e16448Association of rosacea with inflammatory bowel diseaseA MOOSE-compliant meta-analysisWang, Fang-Ying MD, Chi, Ching-Chi MMS, DPhil

"Young men with acne have also been studied with respect to their diet. Smith et al recently studied 43 men (15–25 years) with acne who were given instructions to follow a high carbohydrate diet similar to their current diet (control group) compared to a group given instructions to follow a low glycemic load diet for 12 weeks. There was a significant decrease in the number of acne lesions following diet modification in the low glycemic load group compared to the control group." The Role of Diet in Acne and Rosacea JCAD Online Editor | September 16, 2008 by Jonette E. Keri, MD, PhD, and Adena E. Rosenblatt Department of Dermatology, University of Miami Miller School of Medicine, Miami, Florida

"Ledesma suggested I undergo a micronutrient testing to determine if any supplements could help me to better control my blood sugar and potentially improve my health in other ways. I underwent a blood draw for the SpectraCell Micronutrient Test, a comprehensive test of the biochemical function of vitamins, minerals, amino acids and antioxidants. It seemed like the best way to find out my specific nutritional deficiencies and not take a typical shotgun approach to choosing a wide array of nutrients. The MNT test retails for more than $1,500. I was surprised to find Medicare covered nearly all of it. My cost would be $88. Ledesma said we would balance the nutrients and address any borderline or deficient nutrients." A Patient's Journey: There's a Vitamin for That Howard Wolinsky may have the most expensive urine in Chicago, by Howard Wolinsky, Contributing Writer, MedPage Today

"So I went to see the eye doctor. He prescribed an ocular antibiotic. Then, he hit me with a shocker. Out of left field, he diagnosed rosacea of the eyelid. I knew what rosacea was, but had no clue about rosacea of the eyelid. I was stunned to read how it carried a risk of blindness in extreme cases. I continued my Google research and found an academic ophthalmologist in Chicago, Marian Macsai, MD, at NorthShore University HealthSystem, who had researched rosacea of the eyelid. The thought of potential blindness focuses your attention, which is why -- as an ever cautious individual -- I decided to see her. I had to wait a couple months and almost backed out. I'm glad I didn't. Macsai examined my eyes and immediately concluded I didn't have rosacea of the eyelid. Relief. She stopped the antibiotic, which she said was too powerful.....She recommended a non-prescription special blend of fish oil....I ordered the DE, dry-eye blend, and started taking four capsules a day with meals. I suddenly noticed a change. My eyes stopped itching. I seemed fine." A Patient's Journey: There's a Vitamin for That Howard Wolinsky may have the most expensive urine in Chicago, by Howard Wolinsky, Contributing Writer, MedPage Today

Sensitivity happens when your skin’s natural barrier function becomes compromised, allowing irritants to penetrate it. Sensitivity can be caused by genetics and hormonal factors, having overly dry or injured skin, and excessive exposure to damaging environmental factors such as sun, wind and heat. However, a lot of skin irritations can also be self-inflicted. Excessive cleansing with the incorrect products may also trigger skin sensitivity. Exfoliators containing alphahydroxy acid, for example, may overstimulate the skin and cause microscopic cracks that allow toxins and irritants to enter. Typical breakouts that result from skin sensitivity include eczema, rosacea, primary irritant dermatitis, allergic contact dermatitis or dry flakey skin. Ask Ncumisa: What Causes Skin Sensitivity?, Marie Claire More information on Sensitive Skin Reply to this Topic There is a reply to this topic button somewhere on the device you are reading this post. If you never heard about this topic and you learned about it here first, wouldn't it be a gracious act on your part to show your appreciation for this topic by registering with just your email address and show your appreciation with a post? And if registering is too much to ask, could you post your appreciation for this topic by finding the START NEW TOPIC button in our guest forum where you don't have to register? We know how many have viewed this topic because our forum software shows the number of views. However, most rosaceans don't engage or show their appreciation for our website and the RRDi would simply ask that you show your appreciation, please, simply by a post.

A Rosacea Market Report is available ($5750) that proposed to help in developing business strategies by understanding trends shaping and driving the Rosacea Market. Rosacea Market Research, Growth Opportunities, Analysis and Forecasts Report 2025, MilTech, PR Distribution

"Kern-Lima’s story is truly a self-made American dream. While working as a TV anchor, she had a need—to cover up her very stubborn rosacea—for makeup that would stay on during “air-time.” It was only 9 short years ago that she started her company with a life-changing concealer, and it is with this one product, you can honestly say, that she has transformed what we now know as, “before and after”. Despite two years of countless “no’s” from investors and retailers, she was not discouraged because, in her gut, she believed that “the power of the people was greater than the people in power.” She was able to prove herself right when she got her first 10 minutes of “yes” at QVC, bravely baring her rosacea-prone face in order to show just how well her Bye Bye Under Eye Concealer worked. In ten minutes, she sold out 6000 units—and the rest is history." How to Build A Billion Dollar Beauty Brand in 8 Years We asked Jamie Kern Lima, CEO and Co-Founder of It Cosmetics how she did it. by SUNHEE GRINNELL, Vanity Fair

"Hovione announced today (December 13, 2017) enrollment of the first patient in MARS (Minocycline Against Rosacea Study), a Phase 2 clinical study of topical minocycline (HY01) in moderate to severe papulopustular rosacea patients.....Hovione's minocycline topical gel is a stable, proprietary formulation of crystalline minocycline base and oil-based excipients; in comparison, all minocycline formulations whether in clinical use or currently under clinical development, utilize minocycline hydrochloride as the active ingredient. Hovione has secured patents for both the API and the drug product across the US and the EU with exclusivity through 2033. Minocycline is believed to have superior anti-inflammatory profile as compared to other tetracyclines." Hovione Announces Enrollment of First Patient in MARS, a Phase 2 Clinical Trial for the Treatment of Moderate to Severe Inflammatory Rosacea with its Proprietary Minocycline Topical Gel, Cision PR Newswire Hovione Announces Successful End-of-phase 2 Meeting With the FDA and Outlines Phase 3 Program for Minocycline Topical Gel, Yahoo Finance, Sept. 20, 2019 /PRNewswire/ For the latest update Reply to this Topic There is a reply to this topic button somewhere on the device you are reading this post. If you never heard about this topic and you learned about it here first, wouldn't it be a gracious act on your part to show your appreciation for this topic by registering with just your email address and show your appreciation with a post? And if registering is too much to ask, could you post your appreciation for this topic by finding the START NEW TOPIC button in our guest forum where you don't have to register? We know how many have viewed this topic because our forum software shows the number of views. However, most rosaceans don't engage or show their appreciation for our website and the RRDi would simply ask that you show your appreciation, please, simply by a post.

"According to Dr. Whitney Bowe, probiotics benefit the skin in three key ways. First, they act as a protective shield by preventing bad microorganisms from provoking an immune reaction. “This creates a more calming environment for the skin,” she says. Second, they produce natural antibiotics called antimicrobial peptides that combat bad bacteria. And lastly, they boost the skin’s functionality in dealing with external damaging factors including free radicals, sun, and pollution. “All of these benefits help to reduce inflammation,” she says. “This helps reduce flare-ups and preventing premature aging.” " Why Probiotic Skin Care Is (Actually) Worth It, According to Experts, by LAUREN VALENTI, Vogue Dr. Bowe volunteers on the RRDi MAC.

"This has led some experts to believe acne and rosacea might be made worse by soap, excessive cleanliness, antibiotic use, and anything that alters the normal-flora living on our skin, which protects us from invasive bacteria." Rosacea affects 5 percent of population Richard P. Holm, MD, Argus Leader

"Some chronic rosacea sufferers swear that an under-the-radar cream made from caper-bud extract has relieved them of the painful redness and inflammation caused by the common condition." Could This Controversial Condiment Be The Key To Ending Rosacea? RACHEL KRAUSE, Refinery29

Suyun Li, Ph.D., from Guangzhou Medical University in China, and colleagues used data from 89,886 participants in the Nurses' Health Study II (1991 to 2005) to assess the relationship between obesity and rosacea. The researchers found that over 14 years of follow-up there were 5,249 incident cases of rosacea. The risk for rosacea was higher among those with increased body mass index (BMI; Ptrend < 0.0001). For BMI ≥35.0 kg/m², the hazard ratio of rosacea was 1.48, compared to those with a BMI of 21.0 to 22.9 kg/m². A significantly increased risk for rosacea was seen with higher waist circumference and hip circumference (Ptrend < 0.0001), independent of BMI. "The study contributes to the understanding of rosacea etiology and informs clinical practice related to rosacea prevention and patient care," the authors write. Obesity may be tied to higher rosacea risk in women, Journal of the American Academy of Dermatology, Medical Express

These are the ten most common skin conditions Britons are covering up. - Dry skin - Cold sores - Spots - Eczema - Verrucas - Acne - Greasy skin - Warts - Psoriasis - Rosacea Dry skin warning: 10 conditions Britons ignore - and why that could be dangerous, By LAUREN CLARK, The Daily and Sunday Express

Rosacea can be a very bothersome and embarrassing condition. Untreated rosacea tends to worsen over time. Prompt recognition and proper treatment permit people with rosacea to enjoy life. Doctor’s advice: What is Rosacea?, Estcourt and Midlands News

"The firm is also developing FMX103, a version of its minocycline foam FMX101, which is in Phase II clinical trial for the treatment of rosacea." Foamix Pharmaceuticals (NASDAQ:FOMX) Covered By Yet Another Research Firm December 7, 2017 - By Clifton Ray, Weekly Hub

"By now, you've probably heard of microneedling — a process in which a specialized device is used to create microscopic holes in the skin — and its potential skin-smoothing, scar-reducing, and pigment-fading benefits. And while the treatment has become a highly popular request at the dermatologist's office, many are seeking ways to perform the treatment in the comfort of their own homes, too. Because of this, the Food and Drug Administration might soon be stepping in....."The at-home user may also not be aware of contraindications, such as herpes infection, an acne breakout, a psoriasis flair, a rosacea flair, an open wound, and active skin cancer, or recent chemotherapy," she says. The FDA May Soon Regulate At-Home Microneedling on Skin BY ERIN NICOLE CELLETTI, allure

“It can lead, in many cases, to embarrassment, anxiety, and to depression. So it is not just a physical ailment, but a psychological problem,” Dr. Alejandro Adam, co-founder of Praxis Biotechnology. Frustrated with a lack of treatment options, Drs. Wladis and Adam created their own company to research solutions. It’s called Praxis Biotechnology, and it is based at Albany Medical College. “Our mission is to improve medical practice through scientific research,” said Dr. Adam. They’ve developed a topical medication targeting a specific protein that is found the skin of people with rosacea. “We’re providing a really specific knockout punch for rosacea that as opposed to targeting the immune system in general,” said Wladis. STARTUP DEVELOPS POTENTIALLY GROUNDBREAKING ROSACEA MEDICATION By Terry Stackhouse, Spectrum News

"Rachael Miles, 36, has rosacea, a common long-term and poorly-understood skin condition that mainly affects the face. “As my world collapsed my skin literally erupted into a furious red lumpy mess, which I later discovered was rosacea,” she told Express.co.uk.....Rachael visited her doctor who prescribed her with a topical steroid, Eumovate, which is actually for eczema, another skin condition. Instead of soothing her rosacea it caused it to flare-up further instead. She returned to her GP again and was given more steroids and lotions that all had a similar effect....While on a three-month waiting list to see a skin specialist - and becoming increasing king worried her complexion would never clear up - she began to research online. It was during one of these searches that Rachael stumbled upon Kalme caper products (www.kalme.co.uk), recommended by someone on a rosacea support group website. As well as being moisturising and reducing sensitivity, they have an anti-inflammatory and redness-reducing effect. “They were the first products I had put on that did not burn when I applied them,” she explained. She began applying the products - which are currently priced from £9.95 - to her skin three times a day, and it took just three months for her skin to return to normal." Rosacea treatment BEFORE and after: Woman CURED her skin with £19.95 cream, By LAUREN CLARK, Express Reply to this TopicThere is a reply to this topic button somewhere on the device you are reading this post. If you never heard about this topic and you learned about it here first, wouldn't it be a gracious act on your part to show your appreciation for this topic by registering with just your email address and show your appreciation with a post? And if registering is too much to ask, could you post your appreciation for this topic by finding the START NEW TOPIC button in our guest forum where you don't have to register? We know how many have viewed this topic because our forum software shows the number of views. However, most rosaceans don't engage or show their appreciation for our website and the RRDi would simply ask that you show your appreciation, please, simply by a post.

"One of the reasons clay has remained a staple, especially in masks, is its versatility. According to Dr. Jamé Heskett, author of The Well Path, clay absorbs excess oil, cleanses, exfoliates, improves circulation and binds to toxins. Additionally, clay is able to reduce swelling and inflammation. It’s beneficial for all skin types, including those with rosacea or redness, dull skin, acne and fine lines." 12 Clay Masks That Will Suck Up All the Gunk From Your Pores HEATHER CICHOWSKI,

"Greater purchasing power and higher expenditure on healthcare have also contributed to the growth of these regional markets. Better product availability and an increasing number of companies investing in the field also bode well for the rosacea therapeutics market in North America and Europe." Rosacea Therapeutics Market to See Incredible Growth By 2024, BY PERSISTENCE MARKET RESEARCH, SatPRNews

"Resveratrol is best known as an anti-inflammatory, and it can decrease skin diseases,” says Dr. Lily Talakoub of McLean Dermatology, who notes the positive effects that red wine can have on skin diseases like rosacea and acne. Is Red Wine Good For Your Skin? I Used It As A Face Mask & My Pores Definitely Felt Tighter, By ZOE WEINER, Bustle

The National Rosacea Society is a 501 c 3 non profit organization and according to its about us page is the "world's largest organization dedicated to improving the lives of the estimated 16 million Americans who suffer from this widespread but poorly understood disorder." So who is serving on its board of directors? Not one rosacea sufferer. All the board members are dermatologists or business professionals who have a vested interest in how the NRS spends its donations. So, let's look at how the NRS spends its donations. Follow the money. Do you even care how the NRS spends its donations? Read on if you do. NRS Review of Form 990 for 2016 thru 2020 (scroll down for 2017 in the next post and 2018 in the post after that and so on...) 2016 NRS Form 990 Review Every year for some time now I have been reviewing the NRS Form 990 which posts on its web site (the NRS filed an extension). It is similar to the other reviews I have given in the past (more info). Very few, if any, rosacea sufferers are interested in how the NRS spends its donations nor care at all. As far as I know I am the lone watchdog on the NRS. However, since the NRS was the chief reason the RRDi was formed because we thought donated funds could be better spent than how the NRS spends its donated funds giving rosacea sufferers an alternative, you may see why I continue to monitor and review the NRS spending and post my review. The nutshell version for 2016 is that the NRS received $748,671 in revenue and spent $712,214 in expenses. The NRS spent $65,092 on research grants. So that amounts to 8.69% of its donations. To put this in perspective, every dollar donated in to the NRS in 2016, about 8.6 cents was spent on research grants. 68% ($510,757) of the donations were spent on two private contractors, Glendale Communications Group, Inc. and Park Mailing and Fulfillment, Inc. that are owned by Sam Huff, President of the NRS. Proof that these two corporations are owned by Sam Huff. It was also reported that Sam received $106,774 (from Glendale and Park) in salary while his secretary, Mary Erhard, received $32,253 (from Glendale). These two private corporations are owned by Samuel B Huff, the Director/President of the NRS. For proof, read this post. Here is a breakdown of the Form 990 for 2016: Form 990 Part 1 Revenue Line 8 Contributions and grants $697,448 Line 9 Program service revenue $ 51,000 Line 10 Investment Income $ 223 Total Revenue $748,671 Expenses Line 13 Grants and similar amounts paid $65,092 Line 17 Other expenses $647,122 Total expenses $712,214 Part VII Compensation of Officers, Directors, Trustees, Key Employees, Highest Compensated Employees, and Independent Contractors Section A (1) Samuel B Huff, President Reported compensation from related organizations $106,774 (2) Mary F. Erhard, Secretary Reported compensation from related organizations $ 32,253 Schedule R Part V Transactions with Related Organizations Note 1 m Performance of services or membership or fundraising solicitations for related organization(s) n Sharing of facilities, equipment, mailing lists, or other assets with related organization(s) o Sharing of paid employees with related organization(s) Note 2 (1) Glendale Communications Group, Inc (c) $467,936 (2) Park Mailing and Fulfillment, Inc. (c) $ 42,821 Total Transactions $510,757 nrs_990_2016.pdf For a spreadsheet of all the years reviewed: click here. Form 990 for 1998 Form 990 for 2013 Form 990 for 2014 Form 990 for 2015 More Links Funded exclusively by donations from individuals 1998 - The Banner Year for the NRS

Hi Andrea, Could use a moderator. If not, how about simply posting about your rosacea issues, or comment on any post in the forum. We could use volunteer posters. I sent you an email.

"Senvie is now offering skin care packages for clients with Normal Skin, Combination Skin, Dry Skin, Oily Skin, Mature Skin. In addition, Senvie also just launched a brand new Organic Skin Care line....Senvie also recently launched a new blog that provides audiences with articles on scars, stretch marks, rosacea, pregnancy, hemorrhoids, wrinkles, skin lightening and more." Senvie Skin Care Announces New line of Beauty & Skin Care Products Including Highly Touted Organic Line!, Digital Journal