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Severe Phenotypes 2 and 4

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"A patient with severe papulopustular rosacea (PPR) and severe background erythema responded well to a treatment regimen consisting of a short course of antibiotics in combination with a corticosteroid, followed by monotherapy with isotretinoin. In patients with very severe, inflamed disease, it is necessary to achieve a rapid response with a fast-acting combinatorial treatment regimen to reduce the inflammation. Patients with severe PPR and an inflammatory component can respond rapidly when treated using a multimodal, tailored approach." 

Martin Schaller, who volunteers on the RRDi MAC, and Lena Gonser wrote a paper with above information of treating a female patient with severe Phenoytype 2 and Phenotype 4 (click here for photos) with antibiotics, prednisolone, topical brimonidine, topical metronidazole, and isotretinoin.  

Drugs R D. 2016 Sep; 16(3): 279–283.
Published online 2016 Sep 13. doi:  10.1007/s40268-016-0141-0
PMCID: PMC5045832
PMID: 27623792
A Tailored Approach to the Treatment of a Patient with a Severe Dynamic Manifestation of Rosacea: A Case Report
Martin Schaller and Lena Gonser

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