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Acyclovir for Rosacea


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Acyclovir, an antiviral medication, has been used to treat rosacea and the results according to one paper is "a patient with rosacea who was completely symptom free during two courses of treatment with acyclovir, which was prescribed for the patient’s herpes..." [1]. Acyclovir has been used to treat Pityriasis rosea, a type of skin rash, reported in one paper that may be effective. [2] Nellukas, at RF reports taking two 200 mg tablets twice daily after meals and states, "To my surprise, rosacea started to recede a few days after I started the regimen!!" In post no 16 on 2/4/19 he reports, "Overall, general redness is down 95%, hardened skin is down 98% and papulous pustules down by 100%."

Topical Acylovir

There is a topical Acylovir cream available by prescription. 


Mylan Releases Acyclovir Ointment, a Zovirax Generic for Herpes Treatment

More information on Virus and Rosacea

Acyclovir is listed as one of the Anti-parasitic Prescription Agents For Rosacea.

Anecdotal Reports

Nellukas in this thread reports "I dont even have redness now and consider myself completely cured."

End Notes

[1] American Journal of Clinical Dermatology
December 2017, Volume 18, Issue 6, pp 845–846 • Full Text 
Improvement of Rosacea During Acyclovir Treatment: A Case Report
Zohreh Sadat Badieyan, Sayed Shahabuddin Hosein

[2] J Am Acad Dermatol. 2006 Jan;54(1):82-5.
Use of high-dose acyclovir in pityriasis rosea.
Drago F, Vecchio F, Rebora A.

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