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Artemisinin (ART)


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  • Root Admin

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Artemisia Image Courtesy of Wikimedia Commons

"Artemisinin (ART), an anti-malaria drug, was reported to have several effects including anti-inflammation and anti-angiogenesis activities. However, the role of ART on rosacea remains unclear....ART ameliorated rosacea-like dermatitis by regulating immune response and angiogenesis, indicating that it could represent an effective therapeutic option for patients with rosacea."

Biomedicine & Pharmacotherapy
Volume 117, September 2019, 109181
Artemisinin, a potential option to inhibit inflammation and angiogenesis in rosacea
Xin Yuan, Ji Li, Yangfan Li, Zhili Deng, Lei Zhou, Juan Long,Yan Tang, Zhihong Zuo, Yiya Zhang, Hongfu Xie

Artemesinin is on the list of anti-malaria treatments used for successful rosacea treatment. Technically, artemisinin is not an anti-viral, but an anti-malaria treatment used on Plasmodium falciparum, a protozoa. Hopefully, we will hear of anecdotal reports of Rosaceans using artemisinin for rosacea with positive results. "Artemisinin derivatives are known for their ability to suppress immune reactions such as inflammation." Wikipedia

"Artemisinin is extracted from the plant Artemisia annua, sweet wormwood, a herb employed in Chinese traditional medicine. A precursor compound can be produced using a genetically-engineered yeast, which is much more efficient than using the plant." Wikipedia

Nicholas Bogosian posted about this treatment with a link. 

Artemisinin is available over the counter and considered one of the Anti-parasitic Prescription Agents.

More information on artemisinin

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  • Root Admin

Therefore, KLK5 inhibitors are considered as therapeutic agents for improving the underlying pathophysiology and clinical manifestation of rosacea. Here, we isolated the active constituents of Artemisia lavandulaefolia (A. lavandulaefolia) and investigated their inhibitory effect on KLK5 protease activity.

PubMed RSS Feed - -Chlorogenic Acid Isomers Isolated from Artemisia lavandulaefolia Exhibit Anti-Rosacea Effects In Vitro

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Artemisia lavandulaefolia has been known to use in the traditional medical practices. 

Extract of Artemisia lavandulaefolia Inhibits In Vitro Angiogenesis in Human Umbilical Vein Endothelial Cells

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"Artemisia is a large, diverse genus of plants with between 200 and 400 species belonging to the daisy family Asteraceae. Common names for various species in the genus include mugwort, wormwood, and sagebrush." Wikipedia

 

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