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Phenotype 2 - Persistent Erythema Explained


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Erythema (from the Greek erythros, meaning red) is redness of the skin or mucous membranes, caused by hyperemia (increased blood flow) in superficial capillaries. It occurs with any skin injury, infection, or inflammation. Examples of erythema not associated with pathology include nervous blushes. Wikipedia 
Erythema in rosacea usually involves the Butterfly or T-Zone area of the face. 


Image - Wikipedia Commons

Persistent Facial Erythema (PFE)
Dr. Del Rosso points out that if "...persistent facial erythema (PFE) is the pivotal diagnostic feature of cutaneous rosacea, including in both the presence or absence of papulopustular lesions..."that dermatologists"...Consider the role of PFE in essentially all patients with cutaneous rosacea." [1]

Erythema used to be designated into one subtype along with telangiectasia: Erythematotelangiectatic Rosacea - Subtype 1 (now separated into Phenotype 2 and Phenotype 3). Read this notice about the subtype classification

Treatment for Phenotype 2

End Notes 

[1] Journal of drugs in dermatology: JDD
June 2019 | Volume 18 | Issue 6 | Editorials | 503 | Copyright © June 2019
What Is “PFE”? It May Just Be Time You Found Out….
Del Rosso Q. James DO
JDR Dermatology Research/Thomas Dermatology Las Vegas, NV


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