rss Posted October 5, 2019 Report Share Posted October 5, 2019 Related Articles Treatment of Demodex-Associated Inflammatory Skin Conditions: A Systematic Review. Dermatol Ther. 2019 Oct 03;:e13103 Authors: Jacob S, VanDaele MA, Brown JN Abstract Bacterial folliculitis, rosacea, and other common skin conditions have been linked to infestation by Demodex mites (human demodicosis). Currently, there is little guidance for treatment of inflammatory conditions associated with demodicosis. Thus, the objective of this review is to evaluate the efficacy and safety of treatments utilized for Demodex infestation. Pubmed (1946 to January 2019) and Embase (1947 to January 2019) were searched with the following term combinations: Demodex mites, Demodex folliculitis, demodicosis, Demodex folliculorum, or Demodex brevis and articles evaluating treatment of body surface colonization with Demodex mites were included. Common interventions used for Demodex infestation include metronidazole-based therapies, permethrin, benzoyl benzoate, crotamiton, lindane, and sulfur. Short courses of metronidazole taken orally has shown efficacy in reducing Demodex density. Additionally, topical administration of permethrin daily or twice daily was shown to be efficacious across multiple studies. Crotamiton and benzyl benzoate were also efficacious treatments. Several therapies were associated with mild-to-moderate skin irritation. Due to limited data, no standard of care can be identified at this time. Efficacious treatment options may include permethrin, crotamiton, benzyl benzoate, and oral metronidazole; however, long-term efficacy has not been established. This article is protected by copyright. All rights reserved. PMID: 31583801 [PubMed - as supplied by publisher] {url} = URL to article Link to comment Share on other sites More sharing options...
Root Admin Guide Posted October 6, 2019 Root Admin Report Share Posted October 6, 2019 No mention of ivermectin in the abstract. Wonder if these authors have heard of Soolantra? Link to comment Share on other sites More sharing options...
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