Jump to content

Rosacea linked to systemic cormorbidities including dementia


Guide

Recommended Posts

  • Root Admin

Rosacea is linked to a number of systemic cormobidities including dementia. The number of diseases linked to rosacea continues to grow. Below are some links to dementia and rosacea. 

Medical Xpress • EurekAlert • ScienceDailyJAMA Network • The HospitalistTechTimesMcKnight's

"Recently, an increased interest has been shown in the potential associations between neurodegenerative diseases and rosacea. For example, a nationwide cohort study from Denmark explored the relationship between rosacea and neurodegenerative diseases such as Parkinson’s disease. MMPs are believed to be associated with the neurodegenerative diseases and an increased expression of MMP-1 and MMP-9 has also been observed in rosacea. In addition, another Danish study found that rosacea was significantly associated with dementia, especially Alzheimer disease. AMPs, MMP, and inflammatory cascades, which have a shared impact on both rosacea and Alzheimer disease, are considered to be involved in the underlying mechanism. Together, these findings suggest that a pathogenic link might therefore exist between rosacea and neurodegenerative diseases."
Int J Mol Sci. 2016 Sep; 17(9): 1562.
Published online 2016 Sep 15. doi:  10.3390/ijms17091562, PMCID: PMC5037831
Rosacea: Molecular Mechanisms and Management of a Chronic Cutaneous Inflammatory Condition
Yu Ri Woo, Ji Hong Lim, Dae Ho Cho, and Hyun Jeong Park

More Information on Systemic Cormobidities in Rosacea

Link to comment
Share on other sites

  • 5 months later...
  • Root Admin

"#4 Rosacea
Physical conditions may likewise indicate increased risk for dementia. In one study, individuals who had been diagnosed with rosacea had a 42 percent higher risk for dementia. Rosacea is a skin condition that affects mainly the face. It is characterized by severe redness and blushing of the skin."

Five Symptoms Of Dementia You Need To Know
BY PEACH ANGELES

Link to comment
Share on other sites

  • 4 weeks later...
  • Root Admin

"A Danish study found that patients with rosacea had a seven percent increased chance of developing dementia, and a 25 percent increased chance of developing Alzheimer’s disease. The risk for women with rosacea was greater than for men, at 28 percent compared to 16 percent."

Study Finds Alzheimer’s Disease Is Linked to Rosacea, by Wendy Henderson, Social Clips, Alzheimer's News Today

The Danish study mentioned above is the following: 

Ann Neurol. 2016 Jun;79(6):921-8. doi: 10.1002/ana.24645. Epub 2016 Apr 28.
Patients with rosacea have increased risk of dementia.
Egeberg A, Hansen PR, Gislason GH, Thyssen JP.

Alexander Egeberg, M.D., Ph.D., the lead author in the above study is a member of the RRDi MAC

Link to comment
Share on other sites

  • 2 years later...
  • Administrators
9 hours ago, Mandy Kimber said:

I have just been diagnosed with bvFTD a form of early dementia .... developed rosacea at the beginning of the year when my bvFTD was getting worse, frighening to realise they are linked 

 

Yes they may be linked because roscaea is a kind of chronic inflammatory condition which may or may not be associated with co-morbidities and can occur with other co-expressing conditions. Rosacea can co-exist with other inflammatory conditions. If you are an elderly person and you have been diagnosed with a form of dementia, it is linked to chronic inflammation that means neuroinflammatory condition and neuropeptides are associated with this inflammation because they are the mediators of inflammation and neuropeptides circulate between the brain and peripheral tissues and hence found in the skin and is the cause of your rosacea because chronic skin inflammatory conditions are associated with neuropeptides.

Link to comment
Share on other sites

  • Root Admin
13 hours ago, Mandy Kimber said:

I have just been diagnosed with bvFTD a form of early dementia .... developed rosacea at the beginning of the year when my bvFTD was getting worse, frighening to realise they are linked 

 

Welcome to the RRDi, 

What treatment are you using for your rosacea? Is it working?

Link to comment
Share on other sites

  • Guide pinned this topic

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
×
×
  • Create New...

Important Information

Terms of Use